New Triple-Threat treatment enters final testing for Tough-to-Treat breast cancer

NCT ID NCT04862663

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new drug called capivasertib to two standard breast cancer drugs works better for controlling advanced breast cancer. It will involve about 895 adults whose cancer is hormone receptor-positive, HER2-negative, and has worsened despite prior hormone therapy. The goal is to see if the three-drug combination can slow cancer growth longer than the current two-drug standard.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Research Site
RECRUITING

Tucson, Arizona, 85719, United States
Research Site
RECRUITING

Fountain Valley, California, 92708, United States
Research Site
RECRUITING

Glendale, California, 91204, United States
Research Site
RECRUITING

Los Angeles, California, 90033, United States
Research Site
WITHDRAWN

Los Angeles, California, 90048, United States
Research Site
RECRUITING

Napa, California, 94558, United States
Research Site
SUSPENDED

Newport Beach, California, 92663, United States
Research Site
RECRUITING

San Francisco, California, 94158, United States
Research Site
WITHDRAWN

Santa Barbara, California, 93105, United States
Research Site
RECRUITING

Santa Rosa, California, 92805, United States
Research Site
RECRUITING

Aurora, Colorado, 80045, United States
Research Site
RECRUITING

New Haven, Connecticut, 06510, United States
Research Site
RECRUITING

Newark, Delaware, 19713, United States
Research Site
SUSPENDED

Quincy, Illinois, 62305, United States
Research Site
WITHDRAWN

Fort Wayne, Indiana, 46804, United States
Research Site
WITHDRAWN

Louisville, Kentucky, 40202, United States
Research Site
RECRUITING

Louisville, Kentucky, 40202, United States
Research Site
WITHDRAWN

Baton Rouge, Louisiana, 70809, United States
Research Site
WITHDRAWN

Covington, Louisiana, 70433, United States
Research Site
RECRUITING

Annapolis, Maryland, 21401, United States
Research Site
WITHDRAWN

Baltimore, Maryland, 21202, United States
Research Site
WITHDRAWN

Baltimore, Maryland, 21229, United States
Research Site
RECRUITING

Boston, Massachusetts, 02215, United States
Research Site
RECRUITING

Detroit, Michigan, 48236, United States
Research Site
RECRUITING

Grand Rapids, Michigan, 49503, United States
Research Site
RECRUITING

Hannibal, Missouri, 63401, United States
Research Site
RECRUITING

St Louis, Missouri, 63110, United States
Research Site
RECRUITING

Omaha, Nebraska, 68130, United States
Research Site
RECRUITING

Camden, New Jersey, 08103, United States
Research Site
WITHDRAWN

Brooklyn, New York, 11220, United States
Research Site
RECRUITING

Mineola, New York, 11501, United States
Research Site
RECRUITING

New York, New York, 10016, United States
Research Site
RECRUITING

New York, New York, 10065, United States
Research Site
WITHDRAWN

Durham, North Carolina, 27710, United States
Research Site
RECRUITING

Gresham, Oregon, 97030, United States
Research Site
SUSPENDED

Philadelphia, Pennsylvania, 19104, United States
Research Site
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
Research Site
TERMINATED

York, Pennsylvania, 17403, United States
Research Site
WITHDRAWN

Providence, Rhode Island, 02903, United States
Research Site
TERMINATED

Greenville, South Carolina, 29607, United States
Research Site
RECRUITING

Chattanooga, Tennessee, 37404, United States
Research Site
RECRUITING

Nashville, Tennessee, 37203, United States
Research Site
RECRUITING

Dallas, Texas, 75246, United States
Research Site
WITHDRAWN

Fort Worth, Texas, 76104, United States
Research Site
SUSPENDED

Houston, Texas, 77030, United States
Research Site
RECRUITING

San Antonio, Texas, 78229, United States
Research Site
RECRUITING

San Antonio, Texas, 78240, United States
Research Site
RECRUITING

Salt Lake City, Utah, 84106, United States
Research Site
RECRUITING

Fairfax, Virginia, 22031, United States
Research Site
RECRUITING

Falls Church, Virginia, 22042, United States
Research Site
RECRUITING

Midlothian, Virginia, 23114, United States
Research Site
RECRUITING

Norfolk, Virginia, 23502, United States
Research Site
RECRUITING

Tacoma, Washington, 98405, United States
Research Site
ACTIVE_NOT_RECRUITING

Buenos Aires, 1439, Argentina
Research Site
ACTIVE_NOT_RECRUITING

CABA, 1414, Argentina
Research Site
ACTIVE_NOT_RECRUITING

CABA, 1425, Argentina
Research Site
ACTIVE_NOT_RECRUITING

CABA, C1113AAE, Argentina
Research Site
SUSPENDED

CABA, C1425, Argentina
Research Site
ACTIVE_NOT_RECRUITING

Chivilcoy, B6620LUD, Argentina
Research Site
ACTIVE_NOT_RECRUITING

Rosario, 2000, Argentina
Research Site
WITHDRAWN

Santa Fe, S2002RE, Argentina
Research Site
RECRUITING

Darlinghurst, 2010, Australia
Research Site
WITHDRAWN

Miranda, 2228, Australia
Research Site
ACTIVE_NOT_RECRUITING

Nedlands, 6009, Australia
Research Site
RECRUITING

Nedlands, 6009, Australia
Research Site
WITHDRAWN

Wahroonga, 2076, Australia
Research Site
RECRUITING

Waratah, 2298, Australia
Research Site
RECRUITING

Brasschaat, 2930, Belgium
Research Site
RECRUITING

Brussels, 1200, Belgium
Research Site
RECRUITING

Edegem, 2650, Belgium
Research Site
RECRUITING

Haine-Saint-Paul, 7100, Belgium
Research Site
RECRUITING

Leuven, 3000, Belgium
Research Site
ACTIVE_NOT_RECRUITING

Alfenas, 37130-000, Brazil
Research Site
ACTIVE_NOT_RECRUITING

Blumenau, 89010-340, Brazil
Research Site
ACTIVE_NOT_RECRUITING

Natal, 59075-740, Brazil
Research Site
ACTIVE_NOT_RECRUITING

Porto Alegre, 90035-903, Brazil
Research Site
ACTIVE_NOT_RECRUITING

Porto Velho, 76834-899, Brazil
Research Site
ACTIVE_NOT_RECRUITING

São Paulo, 04014-002, Brazil
Research Site
ACTIVE_NOT_RECRUITING

Taubaté, 12030-200, Brazil
Research Site
ACTIVE_NOT_RECRUITING

Teresina, 64049-200, Brazil
Research Site
ACTIVE_NOT_RECRUITING

Vitória, 29043-260, Brazil
Research Site
RECRUITING

Abbotsford British Columbia, British Columbia, V2S0C2, Canada
Research Site
RECRUITING

Kelowna, British Columbia, V1Y 5L3, Canada
Research Site
WITHDRAWN

Winnipeg, Manitoba, R3E 0V9, Canada
Research Site
WITHDRAWN

Moncton, New Brunswick, E1C 6Z8, Canada
Research Site
RECRUITING

Halifax, Nova Scotia, B3H 1V7, Canada
Research Site
RECRUITING

Brampton, Ontario, L6R 3J7, Canada
Research Site
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
Research Site
WITHDRAWN

Sault Ste. Marie, Ontario, P6A 2C4, Canada
Research Site
RECRUITING

Toronto, Ontario, M5B 1W8, Canada
Research Site
RECRUITING

Sherbrooke, Quebec, J1H 5N4, Canada
Research Site
RECRUITING

Chicoutimi, G7H 5H6, Canada
Research Site
RECRUITING

Montreal, H3T 1E2, Canada
Research Site
ACTIVE_NOT_RECRUITING

Beijing, 100039, China
Research Site
ACTIVE_NOT_RECRUITING

Beijing, 100044, China
Research Site
ACTIVE_NOT_RECRUITING

Beijing, 100191, China
Research Site
ACTIVE_NOT_RECRUITING

Beijing, 100210, China
Research Site
ACTIVE_NOT_RECRUITING

Bengbu, 233004, China
Research Site
ACTIVE_NOT_RECRUITING

Changchun, 130000, China
Research Site
ACTIVE_NOT_RECRUITING

Changsha, 410013, China
Research Site
ACTIVE_NOT_RECRUITING

Chengdu, 610041, China
Research Site
ACTIVE_NOT_RECRUITING

Chongqing, 400042, China
Research Site
ACTIVE_NOT_RECRUITING

Guangzhou, 510060, China
Research Site
ACTIVE_NOT_RECRUITING

Guangzhou, 510062, China
Research Site
WITHDRAWN

Guangzhou, 510080, China
Research Site
ACTIVE_NOT_RECRUITING

Hangzhou, 31000, China
Research Site
WITHDRAWN

Hangzhou, 310016, China
Research Site
ACTIVE_NOT_RECRUITING

Hangzhou, 310022, China
Research Site
ACTIVE_NOT_RECRUITING

Hefei, 230031, China
Research Site
WITHDRAWN

Jinan, 250001, China
Research Site
ACTIVE_NOT_RECRUITING

Nanchang, 330006, China
Research Site
ACTIVE_NOT_RECRUITING

Nanchang, 330009, China
Research Site
ACTIVE_NOT_RECRUITING

Nanjing, 210029, China
Research Site
ACTIVE_NOT_RECRUITING

Nanning, 530021, China
Research Site
ACTIVE_NOT_RECRUITING

Shandong, China
Research Site
ACTIVE_NOT_RECRUITING

Shanghai, 200032, China
Research Site
RECRUITING

Shanghai, 200032, China
Research Site
ACTIVE_NOT_RECRUITING

Shenyang, 110001, China
Research Site
ACTIVE_NOT_RECRUITING

Shenyang, 110016, China
Research Site
WITHDRAWN

Ürümqi, 830000, China
Research Site
ACTIVE_NOT_RECRUITING

Ürümqi, 830000, China
Research Site
ACTIVE_NOT_RECRUITING

Wuhan, 430060, China
Research Site
ACTIVE_NOT_RECRUITING

Xi'an, 710061, China
Research Site
WITHDRAWN

Xi'an, 710100, China
Research Site
WITHDRAWN

Xiangyang, 441000, China
Research Site
ACTIVE_NOT_RECRUITING

Xuzhou, 221009, China
Research Site
ACTIVE_NOT_RECRUITING

Zhengzhou, 450008, China
Research Site
ACTIVE_NOT_RECRUITING

Aalborg, 9000, Denmark
Research Site
ACTIVE_NOT_RECRUITING

Aarhus N, 8200, Denmark
Research Site
ACTIVE_NOT_RECRUITING

Hillerød, 3400, Denmark
Research Site
COMPLETED

Odense, 5000, Denmark
Research Site
RECRUITING

Bobigny, 93000, France
Research Site
RECRUITING

Clermont-Ferrand, 63011, France
Research Site
RECRUITING

Limoges, 87042, France
Research Site
RECRUITING

Lyon, 69008, France
Research Site
RECRUITING

Plérin, 22190, France
Research Site
RECRUITING

Rouen, 76021, France
Research Site
RECRUITING

Saint-Herblain, 44805, France
Research Site
RECRUITING

Villejuif, 94805, France
Research Site
RECRUITING

Augsburg, 86150, Germany
Research Site
WITHDRAWN

Berlin, 10967, Germany
Research Site
RECRUITING

Berlin, 13125, Germany
Research Site
WITHDRAWN

Bottrop, 46236, Germany
Research Site
RECRUITING

Dresden, 01307, Germany
Research Site
RECRUITING

Erlangen, 91054, Germany
Research Site
RECRUITING

Essen, 45136, Germany
Research Site
RECRUITING

Frankfurt am Main, 65929, Germany
Research Site
RECRUITING

Freiburg im Breisgau, 79106, Germany
Research Site
RECRUITING

Georgsmarienhütte, 49124, Germany
Research Site
WITHDRAWN

Hamburg, 20357, Germany
Research Site
RECRUITING

Hanover, 30625, Germany
Research Site
RECRUITING

Heilbronn, 74078, Germany
Research Site
RECRUITING

Kiel, 24105, Germany
Research Site
RECRUITING

Leipzig, 04103, Germany
Research Site
RECRUITING

Mannheim, 68167, Germany
Research Site
RECRUITING

Mönchengladbach, 41061, Germany
Research Site
WITHDRAWN

Münster, 48149, Germany
Research Site
RECRUITING

Regensburg, 93053, Germany
Research Site
WITHDRAWN

Stade, 21680, Germany
Research Site
WITHDRAWN

Trier, 54290, Germany
Research Site
RECRUITING

Ulm, 89075, Germany
Research Site
ACTIVE_NOT_RECRUITING

Bangalore, 560004, India
Research Site
WITHDRAWN

Jaipur, 302017, India
Research Site
WITHDRAWN

Jaipur, 302022, India
Research Site
RECRUITING

Mohali, 160055, India
Research Site
RECRUITING

Mysuru, 570017, India
Research Site
RECRUITING

Nagpur, 440001, India
Research Site
RECRUITING

New Delhi, 110075, India
Research Site
RECRUITING

New Delhi, 110076, India
Research Site
WITHDRAWN

Puducherry, 605006, India
Research Site
RECRUITING

Vadodara, 391760, India
Research Site
RECRUITING

Varanasi, 221005, India
Research Site
WITHDRAWN

Aviano, 33081, Italy
Research Site
RECRUITING

Bologna, 40138, Italy
Research Site
WITHDRAWN

Catanzaro, 88100, Italy
Research Site
RECRUITING

Florence, 50141, Italy
Research Site
WITHDRAWN

Milan, 20132, Italy
Research Site
WITHDRAWN

Milan, 20141, Italy
Research Site
RECRUITING

Misterbianco, 95045, Italy
Research Site
RECRUITING

Naples, 80131, Italy
Research Site
RECRUITING

Padua, 35128, Italy
Research Site
RECRUITING

Prato, 59100, Italy
Research Site
WITHDRAWN

Reggio Emilia, 422122, Italy
Research Site
RECRUITING

Roma, 00168, Italy
Research Site
WITHDRAWN

Rozzano, 20089, Italy
Research Site
ACTIVE_NOT_RECRUITING

Chiba, 260-8717, Japan
Research Site
ACTIVE_NOT_RECRUITING

Chūōku, 104-0045, Japan
Research Site
ACTIVE_NOT_RECRUITING

Chūōku, 104-8560, Japan
Research Site
ACTIVE_NOT_RECRUITING

Hidaka-shi, 350-1298, Japan
Research Site
RECRUITING

Hirakata-shi, 573-1191, Japan
Research Site
ACTIVE_NOT_RECRUITING

Hiroshima, 730-8518, Japan
Research Site
ACTIVE_NOT_RECRUITING

Isehara-shi, 259-1193, Japan
Research Site
ACTIVE_NOT_RECRUITING

Kagoshima, 892-0833, Japan
Research Site
ACTIVE_NOT_RECRUITING

Kōtoku, 135-8550, Japan
Research Site
ACTIVE_NOT_RECRUITING

Kyoto, 606-8507, Japan
Research Site
ACTIVE_NOT_RECRUITING

Matsuyama, 791-0280, Japan
Research Site
NOT_YET_RECRUITING

Nagoya, 464-8681, Japan
Research Site
ACTIVE_NOT_RECRUITING

Naha, 901-0154, Japan
Research Site
RECRUITING

Okayama, 700-8558, Japan
Research Site
ACTIVE_NOT_RECRUITING

Osaka, 541-8567, Japan
Research Site
ACTIVE_NOT_RECRUITING

Ota-shi, 373-8550, Japan
Research Site
ACTIVE_NOT_RECRUITING

Sapporo, 060-8638, Japan
Research Site
ACTIVE_NOT_RECRUITING

Sendai, 980-8574, Japan
Research Site
ACTIVE_NOT_RECRUITING

Shimotsuke-shi, 329-0498, Japan
Research Site
ACTIVE_NOT_RECRUITING

Shinagawa-ku, 142-8666, Japan
Research Site
ACTIVE_NOT_RECRUITING

Shinjuku-ku, 162-8655, Japan
Research Site
ACTIVE_NOT_RECRUITING

Suita-shi, 565-0871, Japan
Research Site
ACTIVE_NOT_RECRUITING

Takasaki-shi, 370-0829, Japan
Research Site
ACTIVE_NOT_RECRUITING

Tsu, 514-8507, Japan
Research Site
ACTIVE_NOT_RECRUITING

Yokohama, 241-8515, Japan
Research Site
RECRUITING

George Town, 10350, Malaysia
Research Site
RECRUITING

Kuala Lumpur, 50586, Malaysia
Research Site
RECRUITING

Kuala Lumpur, 59100, Malaysia
Research Site
RECRUITING

Kuala Selangor, 46050, Malaysia
Research Site
COMPLETED

Kuala Selangor, 62250, Malaysia
Research Site
RECRUITING

Kuching, 93586, Malaysia
Research Site
RECRUITING

Pulau Pinang, 10450, Malaysia
Research Site
WITHDRAWN

Bialystok, 15-027, Poland
Research Site
ACTIVE_NOT_RECRUITING

Bydgoszcz, 85-796, Poland
Research Site
RECRUITING

Gdansk, 80-952, Poland
Research Site
WITHDRAWN

Koszalin, 75-581, Poland
Research Site
ACTIVE_NOT_RECRUITING

Krakow, 31-501, Poland
Research Site
SUSPENDED

Lodz, 90-302, Poland
Research Site
SUSPENDED

Lodz, 91-211, Poland
Research Site
WITHDRAWN

Lublin, 20-090, Poland
Research Site
WITHDRAWN

Rzeszów, 35-326, Poland
Research Site
COMPLETED

Warsaw, 02-781, Poland
Research Site
RECRUITING

Warsaw, 02-781, Poland
Research Site
ACTIVE_NOT_RECRUITING

Goyang-si, 10408, South Korea
Research Site
ACTIVE_NOT_RECRUITING

Seoul, 02841, South Korea
Research Site
ACTIVE_NOT_RECRUITING

Seoul, 03080, South Korea
Research Site
ACTIVE_NOT_RECRUITING

Seoul, 03722, South Korea
Research Site
ACTIVE_NOT_RECRUITING

Seoul, 06273, South Korea
Research Site
ACTIVE_NOT_RECRUITING

Seoul, 06351, South Korea
Research Site
ACTIVE_NOT_RECRUITING

Seoul, 5505, South Korea
Research Site
RECRUITING

Barcelona, 8035, Spain
Research Site
RECRUITING

Granada, 18014, Spain
Research Site
RECRUITING

Lleida, 25198, Spain
Research Site
RECRUITING

Madrid, 28034, Spain
Research Site
RECRUITING

Madrid, 28040, Spain
Research Site
WITHDRAWN

Madrid, 28046, Spain
Research Site
RECRUITING

Málaga, 29010, Spain
Research Site
RECRUITING

Pamplona, 31008, Spain
Research Site
RECRUITING

Santiago de Compostela, 15706, Spain
Research Site
ACTIVE_NOT_RECRUITING

Lund, 221 85, Sweden
Research Site
ACTIVE_NOT_RECRUITING

Solna, 17176, Sweden
Research Site
WITHDRAWN

Vaxjo, 35185, Sweden
Research Site
RECRUITING

Kaohsiung City, 80756, Taiwan
Research Site
RECRUITING

Kaohsiung City, 83301, Taiwan
Research Site
RECRUITING

Taichung, Taiwan
Research Site
RECRUITING

Tainan, 704, Taiwan
Research Site
RECRUITING

Taipei, 10002, Taiwan
Research Site
RECRUITING

Taipei, 10449, Taiwan
Research Site
RECRUITING

Taoyuan District, 333, Taiwan
Research Site
ACTIVE_NOT_RECRUITING

Bangkok, 10210, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Bangkok, 10330, Thailand
Research Site
WITHDRAWN

Bangkok, 10400, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Bangkok, 10400, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Bangkok, 10700, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Chiang Mai, 50200, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Dusit, 10300, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Hat Yai, 90110, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Khon Kaen, 40002, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Lampang, 52000, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Ratchathewi, 10400, Thailand
Research Site
ACTIVE_NOT_RECRUITING

Ankara, 6100, Turkey (Türkiye)
Research Site
ACTIVE_NOT_RECRUITING

Antalya, 07070, Turkey (Türkiye)
Research Site
ACTIVE_NOT_RECRUITING

Cordaleo, 35575, Turkey (Türkiye)
Research Site
ACTIVE_NOT_RECRUITING

Goztepe Istanbul, Turkey (Türkiye)
Research Site
WITHDRAWN

Kayseri, 38039, Turkey (Türkiye)
Research Site
ACTIVE_NOT_RECRUITING

Malatya, 44280, Turkey (Türkiye)
Research Site
ACTIVE_NOT_RECRUITING

Samsun, 55200, Turkey (Türkiye)
Research Site
ACTIVE_NOT_RECRUITING

Guildford, CU2 7XX, United Kingdom
Research Site
ACTIVE_NOT_RECRUITING

London, SE1 9RT, United Kingdom
Research Site
ACTIVE_NOT_RECRUITING

Londonderry, BT47 6SB, United Kingdom
Research Site
ACTIVE_NOT_RECRUITING

Taunton, TA1 5DA, United Kingdom
Research Site
ACTIVE_NOT_RECRUITING

York, YO21 8HE, United Kingdom
Research Site
ACTIVE_NOT_RECRUITING

Can Tho, 900000, Vietnam
Research Site
ACTIVE_NOT_RECRUITING

Hanoi, 100000, Vietnam
Research Site
ACTIVE_NOT_RECRUITING

Ho Chi Minh City, 700000, Vietnam
Research Site
ACTIVE_NOT_RECRUITING

Ho Chi Minh City, 70000, Vietnam
Research Site
ACTIVE_NOT_RECRUITING

Hồ Chí Minh, 700000, Vietnam
Research Site
ACTIVE_NOT_RECRUITING

Vinh, 460000, Vietnam

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED (INOPERABLE) OR METASTATIC BREAST CANCER