New hope for advanced breast cancer patients in drug combination trial

NCT ID NCT02007512

Completed Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding the drug enzalutamide to standard hormone therapy (exemestane) could better control advanced breast cancer. It involved 247 postmenopausal women whose cancer had specific hormone receptors but normal HER2 levels. Researchers compared the combination against exemestane alone to see if it could delay cancer progression longer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

A.O.di Perugia S. Maria Della Misericoridia

Perugia, PG, 06132, Italy
ATTN-Research Pharmacist

Aurora, Colorado, 80045, United States
Abbott Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Allina Health System DBA Virginia Piper Cancer Institute

Minneapolis, Minnesota, 55407, United States
Azienda Ospedaliera S.Orsola Malpighi

Bologna, 40138, Italy
Barnes-Jewish Hospital

St Louis, Missouri, 63110, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Brighton and Sussex University Hospital NHS Trust

Brighton, England, BN2 5BE, United Kingdom
Cancer Clinical Trials Unit

Dublin, D9, Ireland
Centro Integral Oncologico Clara Campal

Madrid, 28050, Spain
Clinical Investigation & Research Unit

Brighton, Sussex, BN2 5BE, United Kingdom
Dana-Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Department of Radiology

Truro, England, TR1 3LJ, United Kingdom
Dipartimento di Oncologia Medica, Istituto Nazionale Tumori Regina Elena

Roma, 00144, Italy
Divisione di Senologia Medica; Istituto Europeo di Oncologia

Milan, MI, 20141, Italy
Dr.Michaela Tsai

Minneapolis, Minnesota, 55407, United States
Florida Cancer Specialists

Altamonte Springs, Florida, 32701, United States
Florida Cancer Specialists

Bonita Springs, Florida, 34135, United States
Florida Cancer Specialists

Bradenton, Florida, 34209, United States
Florida Cancer Specialists

Brandon, Florida, 33511, United States
Florida Cancer Specialists

Cape Coral, Florida, 33909, United States
Florida Cancer Specialists

Clearwater, Florida, 33761, United States
Florida Cancer Specialists

Englewood, Florida, 34223, United States
Florida Cancer Specialists

Fort Myers, Florida, 33901, United States
Florida Cancer Specialists

Fort Myers, Florida, 33905, United States
Florida Cancer Specialists

Fort Myers, Florida, 33908, United States
Florida Cancer Specialists

Gainesville, Florida, 32605, United States
Florida Cancer Specialists

Hudson, Florida, 34667, United States
Florida Cancer Specialists

Largo, Florida, 33770, United States
Florida Cancer Specialists

Naples, Florida, 34102, United States
Florida Cancer Specialists

New Port Richey, Florida, 34655, United States
Florida Cancer Specialists

Orange City, Florida, 32763, United States
Florida Cancer Specialists

Orlando, Florida, 32806, United States
Florida Cancer Specialists

Port Charlotte, Florida, 33980, United States
Florida Cancer Specialists

Sarasota, Florida, 34232, United States
Florida Cancer Specialists

Sarasota, Florida, 34236, United States
Florida Cancer Specialists

Spring Hill, Florida, 34608, United States
Florida Cancer Specialists

St. Petersburg, Florida, 33705, United States
Florida Cancer Specialists

Tampa, Florida, 33607, United States
Florida Cancer Specialists

Tavares, Florida, 32778, United States
Florida Cancer Specialists

Venice, Florida, 34285, United States
Florida Cancer Specialists

Venice, Florida, 34292, United States
GZA

Wilrijk, Antwerpen, 2610, Belgium
Greenville Health System

Greenville, South Carolina, 29605, United States
Greenville Health System

Seneca, South Carolina, 29672, United States
Greenville Health System

Spartanburg, South Carolina, 29307, United States
Grupo Hospitalario Quiron - Hospital Universitari Quiron Dexeus

Barcelona, 08028, Spain
Hematology Oncology Associates of Northern NJ

Morristown, New Jersey, 07962, United States
Henry-Joyce Cancer Clinic

Nashville, Tennessee, 37232, United States
Histopathology Department

Nottingham, England, NG5 1PB, United Kingdom
Hospital Universitari Vall d'Hebron

Barcelona, 08035, Spain
Hospital Universitario 12 Octubre

Madrid, 28041, Spain
Hospital Universitario HM Monteprincipe

Boadilla del Monte, Madrid, 28660, Spain
Hospital Universitario Ramon Y Cajal

Madrid, 28034, Spain
Hospital de Madrid Norte Sanchinarro

Madrid, 28050, Spain
IRCCS Ospedale San Raffaele

Milan, MI, 20132, Italy
Indiana University Health Hospital

Indianapolis, Indiana, 46202, United States
Indiana University Health Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Institut Jules Bordet

Brussels, 1000, Belgium
Institute for Cancer Research

Dublin, 7, Ireland
Institute for Cancer Research

Dublin, Ireland
Investigational Drug Services

Indianapolis, Indiana, 46202, United States
Mater Private Hospital

Dublin, 7, Ireland
Mater Private Hospital

Dublin, Ireland
McGill University Health Center- Cedars Cancer Center

Montreal, Quebec, H4A 3J1, Canada
McGill University Health Centre - Cedars Cancer Centre

Montreal, Quebec, H4A 3J1, Canada
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Minnesota Oncology Hematology, P.A

Minneapolis, Minnesota, 55404, United States
Northwestern Medical Faculty Foundation

Chicago, Illinois, 60611, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Nottingham University Hospital

Nottingham, England, NG5 1PB, United Kingdom
Oncology Hematology Care, Inc.

Cincinnati, Ohio, 45202, United States
Oncology Hematology Care, Inc.

Cincinnati, Ohio, 45211, United States
Oncology Hematology Care, Inc.

Cincinnati, Ohio, 45230, United States
Oncology Hematology Care, Inc.

Cincinnati, Ohio, 45236, United States
Oncology Hematology Care, Inc.

Cincinnati, Ohio, 45242, United States
Oncology Hematology Care, Inc.

Fairfield, Ohio, 45014, United States
Pharmacy Department

Dublin, 4, Ireland
Pharmacy Department

Dublin, 7, Ireland
Pharmacy Department

Dublin, D9, Ireland
Pharmacy Department

Dublin, Ireland
Pharmacy Department

Brighton, England, BN2 5BE, United Kingdom
Pharmacy Department

Nottingham, England, NG5 1PB, United Kingdom
Pharmacy Department

Truro, England, TR1 3LJ, United Kingdom
Radiation Safety Service, Medical Physics Department

Brighton, England, BN2 5BE, United Kingdom
Radiology Department

Dublin, 4, Ireland
Radiology Department

Dublin, 7, Ireland
Radiology Department

Dublin, D9, Ireland
Radiology Department

Dublin, Ireland
Radiology Department

Nottingham, England, NG5 1PB, United Kingdom
Radiology Department

Nottingham, England, NG7 2UH, United Kingdom
Rocky Mountain Cancer Centers

Colorado Springs, Colorado, 80907, United States
Rocky Mountain Cancer Centers

Lakewood, Colorado, 80228, United States
Rocky Mountain Cancer Centers

Lone Tree, Colorado, 80124, United States
Royal Cornwall Hospitals NHS trust

Truro, England, TR1 3LJ, United Kingdom
Sidney and Lois Eskenazi Hospital

Indianapolis, Indiana, 46202, United States
Siteman Cancer Center

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center- West County

St Louis, Missouri, 63141, United States
Siteman Cancer Center-South County

St Louis, Missouri, 63129, United States
Springmill Medical Clinic

Indianapolis, Indiana, 46290, United States
St Vincent's University Hospital

Dublin, 4, Ireland
Sunnybrook Research Institute

Toronto, Ontario, M4N 3M5, Canada
Tennessee Oncology, PLLC

Franklin, Tennessee, 37067, United States
Tennessee Oncology, PLLC

Gallatin, Tennessee, 37066, United States
Tennessee Oncology, PLLC

Hermitage, Tennessee, 37076, United States
Tennessee Oncology, PLLC

Lebanon, Tennessee, 37090, United States
Tennessee Oncology, PLLC

Murfreesboro, Tennessee, 37129, United States
Tennessee Oncology, PLLC

Nashville, Tennessee, 37203, United States
Tennessee Oncology, PLLC

Nashville, Tennessee, 37207, United States
Tennessee Oncology, PLLC

Nashville, Tennessee, 37211, United States
Tennessee Oncology, PLLC

Shelbyville, Tennessee, 37160, United States
Tennessee Oncology, PLLC

Smyrna, Tennessee, 37167, United States
Texas Oncology - Memorial City

Houston, Texas, 77024, United States
Texas Oncology - Tyler

Tyler, Texas, 75702, United States
Texas Oncology-Longview Cancer Center

Longview, Texas, 75601, United States
The Sarah Cannon Research Institute

Nashville, Tennessee, 37203, United States
The University of Chicago

Chicago, Illinois, 60637, United States
The University of Chicago Medical Center,

Chicago, Illinois, 60637, United States
The West Clinic, P.C.

Corinth, Mississippi, 38834, United States
The West Clinic, P.C. d/b/a West Cancer Center

Southaven, Mississippi, 38671, United States
The West Clinic, P.C. d/b/a West Cancer Center

Germantown, Tennessee, 38138, United States
The West Clinic, P.C. d/b/a West Cancer Center

Memphis, Tennessee, 38104, United States
U.O. Farmaceutica, Nuovo Ospedale di Prato

Prato, 59100, Italy
U.O. Oncologia Medica, Nuovo Ospedale di Prato

Prato, 59100, Italy
UZA

Edegem, Antwerpen, 2650, Belgium
University of Chicago Comprehensive Cancer Center at Silver Cross Hospital

New Lenox, Illinois, 60451, United States
University of Colorado Cancer Center - Anschutz Cancer Pavilion

Aurora, Colorado, 80045, United States
University of Colorado Hospital, Anschutz Outpatient Pavilion

Aurora, Colorado, 80045, United States
Vanderbilt Breast Center at One Hundred Oaks

Nashville, Tennessee, 37204, United States
Vanderbilt Health Pharmacy One Hundred Oaks

Nashville, Tennessee, 37204, United States
Virginia Cancer Institute

Mechanicsville, Virginia, 23116, United States
Virginia Cancer Institute

Richmond, Virginia, 23230, United States
Virginia Cancer Institute

Richmond, Virginia, 23235, United States
Washington University Infusion Center Pharmacy

St Louis, Missouri, 63110, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.

BREAST CANCER