Sound waves aim to quiet chronic pain in new brain study

NCT ID NCT06628180

First seen Apr 06, 2026 · Last updated May 16, 2026 · Updated 5 times

Summary

This study explores whether low-intensity focused ultrasound (LIFU) can temporarily change brain activity to reduce chronic pain. About 80 adults with moderate-to-severe pain lasting at least 3 months will receive noninvasive brain stimulation and rate their pain during heat tests. Researchers will also monitor brain signals, heart rate, and quality of life over 10 weeks. The goal is to understand if this safe, sound-wave approach could become a new treatment option.

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Contacts and locations

Locations

  • Fralin Biomedical Research Institute at VTC

    Roanoke, Virginia, 24016, United States

Conditions

Explore the condition pages connected to this study.