New hope for kids with tough brain tumors: testing a Triple-Threat drug combo
NCT ID NCT04201457
Summary
This study is testing whether adding the drug hydroxychloroquine to two other targeted cancer drugs can better control brain tumors in children and young adults. It is for patients whose tumors have grown back or progressed despite previous similar treatments and who have specific genetic changes (BRAF mutations or NF1). The main goals are to find the safest dose and see if this combination can shrink tumors or stop them from growing.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90026, United States
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Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010-2970, United States
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Cincinnati Children Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Lucile Packard Children's Hospital at Stanford University Medical Center
Palo Alto, California, 94304, United States
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Lurie Children's Hospital-Chicago
Chicago, Illinois, 60614, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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National Cancer Institute Pediatric Oncology Branch
Bethesda, Maryland, 20892, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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St. Jude Children Research Hospital
Memphis, Tennessee, 38105, United States
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Texas Children's Cancer Center
Houston, Texas, 77030, United States
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University of Florida
Gainesville, Florida, 32608, United States
Conditions
Explore the condition pages connected to this study.