Early trial probes new drugs for tough brain tumors
NCT ID NCT03343197
Summary
This early-stage study tested two drugs, AG-120 and AG-881, in adults with a recurring, slow-growing brain tumor that has a specific genetic change (IDH1 mutation). The main goal was to see if taking one of these drugs before planned surgery could lower levels of a harmful chemical (2-HG) produced by the tumor. Researchers also checked the safety of the drugs and how the body processes them.
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Contacts and locations
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Locations
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United States, California
Los Angeles, California, 90024, United States
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United States, California
San Francisco, California, 94143, United States
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United States, Massachusetts
Boston, Massachusetts, 02215, United States
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United States, New York
New York, New York, 10065, United States
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United States, North Carolina
Durham, North Carolina, 27710, United States
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United States, Texas
Dallas, Texas, 75390, United States
Conditions
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