Brain zaps and feedback may reboot hand control after paralysis

NCT ID NCT06989905

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests whether a 10-week brain stimulation and feedback training program can strengthen the connection between the brain and wrist muscles in people with chronic cervical spinal cord injury. Eleven adults with weak wrist extension will receive non-invasive brain stimulation while trying to increase a muscle response, with the goal of improving arm and hand function. Researchers will also use MRI scans to understand how the brain and spinal cord change with training.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

brain stimulation and feedback training (operant conditioning of motor evoked potential)

What this could lead to

If it works, this could point toward a non-invasive way to improve arm and hand function after spinal cord injury.

What could go wrong

This is a very early, small trial (11 people) testing a new training approach. It may not produce meaningful improvements, and results may not apply to everyone with spinal cord injury.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Neurologic Manifestations quadriplegia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact