Scientists map brain connections in rare movement disorders

This study aimed to understand how two key brain areas—the basal ganglia and cerebellum—interact in people with specific genetic forms of dystonia, a movement disorder. Researchers compared brain scans from 104 participants, including patients with ADCY5 or PRRT2 gene mutations and healthy volunteers. They used functional MRI and mild, non-invasive brain stimulation to see if stimulating the cerebellum changes activity in other motor control networks.