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New brain zapping technique could unlock deep brain treatments

NCT ID NCT07593859

Knowledge-focused Sponsor: Northeastern University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new type of brain stimulation called transcranial Temporal Interference Stimulation (tTIS) in 30 healthy adults. The goal is to understand how it works by applying it over the motor cortex and measuring brain activity. This research could help improve future treatments for brain disorders.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial Temporal Interference Stimulation (tTIS) device
What this could lead to
If successful, this could help refine tTIS for future use in treating brain disorders like depression or Parkinson's disease.
What could go wrong
This is a small, early-phase study in healthy people, so results may not apply to patients. The technique is still experimental and may not produce lasting effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Oct 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Free of neurological or orthopedic conditions that may impact the ability to participate. * Right-hand dominant (self-reported) * Aged 18-65 years Exclusion Criteria: * Ferromagnetic metal implants in the brain/skull or elsewhere (dental implants excluded). * Any implanted electronic device (e.g. cardiac pacemaker, cochlear implant, deep brain stimulator, medication infusion pump; vagal nerve stimulator) * Diseased or damaged skin on face or scalp * History of migraines, fainting, seizures/epilepsy, or psychiatric illness * Neurological disorder or intracranial lesion * Frequent or severe headaches * Prior adverse reaction to transcranial magnetic stimulation * Currently pregnant * Suspected or diagnosed heart problems (e.g. arrhythmia, cardiac disturbances). * Insulin-dependent diabetes * Suspected or diagnosed epilepsy or a familial history of epilepsy * Use of alcohol or recreational drugs in the prior 12 hours * Use of prescription and over the counter medications will be grounds for exclusion except for: contraceptive (birth control) drugs (e.g. those containing ethinyl estradiol and/or norethindrone), and seasonal allergy medications (e.g. cetirizine (Zyrtec), fexofenadine (Allegra), and loratadine (Claritin)).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy adult participants

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Northeastern University

    RECRUITING

    Boston, Massachusetts, 02115-5724, United States

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