Brain zapping and training may unlock secrets of OCD
NCT ID NCT04580043
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether non-invasive brain stimulation combined with computer-based training can change brain activity and reduce compulsive behaviors in people with OCD. 203 adults with problematic compulsions participated. The goal was to understand how a specific brain region (the orbitofrontal cortex) is involved in compulsive habits, which could lead to better treatments in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcranial Magnetic Stimulation (brain stimulation) and computerized brain training
What this could lead to
If successful, this research could point toward new ways to treat compulsive behaviors by targeting specific brain regions.
What could go wrong
This is an early-stage study focused on understanding brain mechanisms, not testing a treatment. The results may not lead directly to new therapies.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, 15213, United States