Brain pacemaker trial offers hope for untreatable depression

NCT ID NCT06423430

Summary

This study is testing whether a surgically implanted brain stimulation device can help adults with severe depression that hasn't improved with multiple medications. Researchers will compare active stimulation to a sham (inactive) treatment in 100 participants over 12 months. The goal is to see if this 'brain pacemaker' can safely reduce depression symptoms and improve quality of life for people who have exhausted other options.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for TREATMENT RESISTANT DEPRESSION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHI St. Luke's Health Baylor College of Medicine Med. Ctr

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Indiana University

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Email: •••••@•••••

    Contact

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mount Sinai Hospital

    RECRUITING

    New York, New York, 10019, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Pennsylvania Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Robert Wood Johnson University Hospital

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Methodist Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact Email: •••••@•••••

    Contact

  • The Ohio State University

    NOT_YET_RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UCLA Department of Psychiatry

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • USC University Hospital

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • USF Health

    RECRUITING

    Tampa, Florida, 33613, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Alabama at Birmingham - Dept. of Psychiatry

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California at Davis

    RECRUITING

    Sacramento, California, 95817, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Chicago

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Minnesota Medical Center Fairview

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Southwestern Medical Center at Dallas

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Utah Hospital

    RECRUITING

    Salt Lake City, Utah, 84132, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.