Brain scans may reveal how drug works in teens with eating disorders

NCT ID NCT05509257

First seen Jan 11, 2026 · Last updated Jun 11, 2026 · Updated 29 times

Summary

This early-phase study aims to see if functional MRI (fMRI) can detect changes in brain reward areas when teens with eating disorders (like bulimia or binge eating) take naltrexone, a drug that blocks opioid receptors. About 60 participants aged 13-21 will receive both naltrexone and a placebo in random order, and their brain activity will be compared. The goal is to develop a biomarker for future treatment studies, not to directly treat the eating disorder.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Children's Mercy Research Institute

    RECRUITING

    Kansas City, Missouri, 64108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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