New study tracks newborn brain health during surgery

NCT ID NCT05673499

Recruiting now Knowledge-focused Sponsor: Children's Hospital of Philadelphia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study monitors brain oxygen levels and electrical activity in 900 newborns undergoing surgery for birth defects. Using special sensors, researchers track changes before, during, and after surgery to understand when the brain may not get enough oxygen. The goal is to identify factors that lead to low brain oxygen and improve safety for future surgeries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better protect newborns' brains during surgery by identifying when oxygen levels drop and what causes it.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly change care yet. Results may not apply to all newborns or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL DESATURATION CONGENITAL DISORDERS NEONATAL SURGERY

Contacts and locations

Locations

Centre Hospitalier Universitaire de Bordeaux, Hopital des enfants
NOT_YET_RECRUITING

Bordeaux, France
Children's Hospital at Montefiore/Albert Einstein College of Medicine
NOT_YET_RECRUITING

New York, New York, 10467, United States
Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Children's Medical Center Dallas
NOT_YET_RECRUITING

Dallas, Texas, 75235, United States
Children's Memorial Hermann Hospital
NOT_YET_RECRUITING

Houston, Texas, 77030, United States
Christian Medical College Hospital
NOT_YET_RECRUITING

Vellore, India
Great Ormond Street Hospital for Children
NOT_YET_RECRUITING

London, United Kingdom
Guangzhou women and children's medical center
NOT_YET_RECRUITING

Guangzhou, China
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
RECRUITING

São Paulo, Brazil
Perth Children's Hospital
RECRUITING

Nedlands, Australia
Post Graduate Institute of Medical Education and Research
NOT_YET_RECRUITING

Chandigarh, India
Royal Children's Hospital
NOT_YET_RECRUITING

Parkville, Australia
Shanghai Children's Medical Center
NOT_YET_RECRUITING

Shanghai, China
Shengjing Hospital of China Medical University
NOT_YET_RECRUITING

Shenyang, China
West China Hospital and West China Second University Hospital
NOT_YET_RECRUITING

Sichuan, China

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