Promising combo for brain metastases halted early

NCT ID NCT04791384

First seen Mar 31, 2026 · Last updated May 15, 2026 · Updated 7 times

Summary

This study tested a combination of two drugs, abemaciclib and elacestrant, in women with a type of breast cancer (HR+/Her2-) that had spread to the brain. The goal was to see if the drugs could shrink brain tumors and control the disease. Only 5 people enrolled before the study was stopped early. The results may help researchers understand how to treat this hard-to-reach cancer.

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Contacts and locations

Locations

  • Cancer Care Northwest

    Spokane Valley, Washington, 99216, United States

  • Duke Cancer Center

    Durham, North Carolina, 27710, United States

  • Mount Sinai Comprehensive Cancer Center

    Miami Beach, Florida, 33140, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.