Tiny radiation tiles placed during brain surgery tested against standard treatment

NCT ID NCT04365374

Summary

This study compares two ways to deliver radiation after surgery to remove brain tumors that have spread from cancer elsewhere in the body. It tests whether placing small, dissolvable radiation tiles (GammaTile) directly in the tumor cavity during surgery works better than the standard approach of delivering focused radiation (SRT) a few weeks later. The main goal is to see which method better prevents the tumor from growing back at the surgical site while maintaining patients' quality of life and thinking abilities.

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Contacts and locations

Locations

  • Abbott Northwestern Hospital

    Minneapolis, Minnesota, 55407, United States

  • Advent health Orlando

    Orlando, Florida, 32804, United States

  • Albany Medical Center

    Albany, New York, 12208, United States

  • Allegheny Health Network

    Pittsburgh, Pennsylvania, 15212, United States

  • Ascension St. Vincent's- Riverside

    Jacksonville, Florida, 32204, United States

  • Baptist MD Anderson Cancer Center- Jacksonville

    Jacksonville, Florida, 32207, United States

  • Baylor St. Luke's Medical Center | Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Brown University Health

    Providence, Rhode Island, 02906, United States

  • Dartmouth-Hitchcock

    Lebanon, New Hampshire, 03766, United States

  • ECU Health

    Greenville, North Carolina, 27834, United States

  • Ellis Fischel Cancer Center at University of Missouri

    Columbia, Missouri, 65212, United States

  • Florida Health Sciences Center, Inc. d/b/a Tampa General Hospital

    Tampa, Florida, 33606, United States

  • HCA Florida First Coast Neurology- Orange Park

    Orange Park, Florida, 32073, United States

  • HMH Jersey Shore University Medical Center

    Neptune City, New Jersey, 07753, United States

  • Henry Ford Health

    Detroit, Michigan, 48202, United States

  • HonorHeath Scottsdale Osborn Medical Center

    Phoenix, Arizona, 85027, United States

  • Houston Methodist

    Houston, Texas, 77030, United States

  • Indiana University, IU Health Methodist Hospital

    Indianapolis, Indiana, 46202, United States

  • Mayfield Brain and Spine

    Cincinnati, Ohio, 45209, United States

  • Memorial Sloan Kettering

    New York, New York, 10065, United States

  • Orlando Health

    Orlando, Florida, 32806, United States

  • Piedmont Hospital

    Atlanta, Georgia, 30309, United States

  • RUSH University

    Chicago, Illinois, 60607, United States

  • SCRI with Texas Oncology

    The Woodlands, Texas, 77380, United States

  • SSM Health Saint Louis University Hospital

    St Louis, Missouri, 63110, United States

  • The University Of Kansas Cancer Center

    Kansas City, Kansas, 66016, United States

  • The University of Texas M. D. Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UT Health San Antonio

    San Antonio, Texas, 78249, United States

  • UT Southwestern Simmons Cancer Center

    Dallas, Texas, 75235, United States

  • University Of Minnesota

    Minneapolis, Minnesota, 55414, United States

  • University of Arkansas Medical Center

    Little Rock, Arkansas, 72205, United States

  • University of Louisville

    Louisville, Kentucky, 40202, United States

  • University of North Carolina Health

    Chapel Hill, North Carolina, 27599, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Virginia Mason

    Seattle, Washington, 98101, United States

  • Westchester Medical Center

    Westchester, New York, 10595, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.