Scientists scan brains of depressed people to find missing enzyme
NCT ID NCT05703685
First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 32 times
Summary
This study uses a special PET scan to measure levels of an enzyme called PDE4B in the brains of people with major depressive disorder (MDD) and healthy volunteers. Researchers want to see if people having a depressive episode have lower PDE4B levels. The study involves up to 5 visits, including brain MRI and PET scans, and may help understand the biology of depression.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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