Scientists scan brains to unlock secrets of rare mitochondrial disease
NCT ID NCT06890520
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study uses MRI brain scans to measure chemicals like glutathione in people with primary mitochondrial disease, a genetic disorder that affects energy production and can damage the brain. Researchers will compare 30 participants with the disease to healthy volunteers to see if chemical imbalances are linked to the condition. The goal is to better understand the disease, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify brain chemical changes that serve as markers for mitochondrial disease, potentially guiding future treatments.
What could go wrong
This is a small, early observational study with only 30 participants, so results may not apply broadly. It does not test any treatment, so no direct benefit is expected.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••