Brain cancer breakthrough? radiation during surgery trial aims to extend lives

NCT ID NCT02685605

Summary

This large Phase 3 trial is testing if adding a single, high dose of radiation directly to the tumor site during surgery helps people with newly diagnosed glioblastoma live longer without their cancer worsening. It compares standard post-surgery radiation and chemotherapy to the same treatment plus this one-time intraoperative boost. The goal is to see if this combined approach better controls this aggressive brain tumor.

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Contacts and locations

Locations

  • Barrow Neurological Institute (SJHMC)

    Phoenix, Arizona, 85013, United States

  • Beijing Tian Tan Hospital, Capital Medical University

    Beijing, 100050, China

  • Catalan Institute of Oncology (ICO)

    Barcelona, 08908, Spain

  • Charité - Universitätsmedizin

    Berlin, 13353, Germany

  • Gangnam Severance Hospital, Yonsei University College of Medicine

    Seoul, 06273, South Korea

  • Helios University Hospital Wuppertal

    Wuppertal, 42283, Germany

  • Hospital Alemão Oswaldo Cruz

    São Paulo, 01323-020, Brazil

  • Hospital Reina Sofia

    Córdoba, Spain

  • Klinikum Stuttgart

    Stuttgart, 70174, Germany

  • Lenox Hill Hospital, Hofstra Northwell School of Medicine

    New York, New York, 10028, United States

  • Long Island Jewish Medical Center, North Shore University Hospital

    Lake Success, New York, 11042, United States

  • Montreal Neurological Institute and Hospital

    Montreal, Quebec, H3A 2B4, Canada

  • St. Georg Hospital

    Leipzig, Germany

  • Stritch School of Medicine Loyola University

    Maywood, Illinois, 60153, United States

  • Technical University of Munich (TUM), Department of Radiation Oncology

    Munich, 81675, Germany

  • The London Clinic

    London, W1G 6BW, United Kingdom

  • University Hospital Augsburg

    Augsburg, 86156, Germany

  • University Hospital Mannheim

    Mannheim, 68167, Germany

  • West Virginia University

    Morgantown, West Virginia, 26506-9260, United States

Conditions

Explore the condition pages connected to this study.