Researchers launch study to track Real-World outcomes in BRAF-Mutated colorectal cancer

NCT ID NCT05639413

Recruiting now Knowledge-focused Sponsor: UNICANCER Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is collecting medical information and blood samples from 400 people with metastatic colorectal cancer that has a specific genetic change called BRAFV600E. The goal is to learn more about how this cancer is treated in everyday practice and what outcomes patients experience. Participants will provide blood samples at various timepoints, and researchers will follow their health over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help researchers better understand how BRAFV600E metastatic colorectal cancer behaves and how it is currently treated in real-world settings.
What could go wrong: This is an observational study, not a treatment trial. It will not test a new therapy or directly improve patient outcomes. Results may take years to influence clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAF V600E MUTATION POSITIVE METASTATIC COLORECTAL CANCER

Contacts and locations

Locations

Aphp - Hopital Bichat
RECRUITING

Paris, 75013, France
Aphp - Hopital Henri Mondor
RECRUITING

Créteil, France
Aphp - Hopital Saint Louis
RECRUITING

Paris, 75010, France
Aphp - La Pitie Salpetriere
RECRUITING

Paris, 75013, France
CH Dr TECHER
ACTIVE_NOT_RECRUITING

Calais, 62107, France
CH Fleyriat
ACTIVE_NOT_RECRUITING

Bourg-en-Bresse, 01000, France
CH Louis Pasteur
NOT_YET_RECRUITING

Le Coudray, 28630, France
CHR d'Orléans
ACTIVE_NOT_RECRUITING

Orléans, 45100, France
Centre Antoine Lacassagne
RECRUITING

Nice, France
Centre Hospitalier D'Avignon
ACTIVE_NOT_RECRUITING

Avignon, 84000, France
Centre Hospitalier de Bayeux
RECRUITING

Bayeux, 14400, France
Centre Leon Berard
RECRUITING

Lyon, 69008, France
Centre Paul Strauss
RECRUITING

Strasbourg, 67033, France
Centre d'Oncologie Saint Yves
RECRUITING

Vannes, 56000, France
Ch Perpignan
RECRUITING

Perpignan, France
Ch de Cahors
RECRUITING

Cahors, France
Ch de Saint Malo
ACTIVE_NOT_RECRUITING

St-Malo, France
Chru de Nancy
RECRUITING

Vandœuvre-lès-Nancy, 54500, France
Chu Dupuytren
RECRUITING

Limoges, 87042, France
Chu Estaing de Clermont-Ferrand
RECRUITING

Clermont-Ferrand, 63003, France
Chu Poitiers
RECRUITING

Poitiers, 86021, France
Chu Rennes Pontchaillou
RECRUITING

Rennes, 35000, France
Chu Simone Veil
ACTIVE_NOT_RECRUITING

Beauvais, France
Chu de Grenoble Alpes - Hopital Michallon
WITHDRAWN

La Tronche, 38700, France
Chu de Reims
RECRUITING

Reims, 51100, France
Chu de Rouen
RECRUITING

Rouen, 76031, France
Chu de Tours
RECRUITING

Tours, 37044, France
GHPSO
RECRUITING

Creil, France
Gh Diaconesses Croix Saint Simon
RECRUITING

Paris, 75020, France
Grand Hopital de L'Est Francilien - Site de Meaux
ACTIVE_NOT_RECRUITING

Meaux, France
Groupe Hospitalier Emile Roux
RECRUITING

Le Puy-en-Velay, France
Groupe Hospitalier Mutualiste de Grenoble
WITHDRAWN

Grenoble, 38028, France
Hnia Begin
ACTIVE_NOT_RECRUITING

Saint-Mandé, France
Hnia Saint Anne
NOT_YET_RECRUITING

Toulon, France
Hopital Europeen Georges Pompidou
RECRUITING

Paris, France
Hopital Franco-Britannique
ACTIVE_NOT_RECRUITING

Levallois-Perret, 92300, France
Hopital Saint Antoine
RECRUITING

Paris, 75012, France
Hopital de La Timone
NOT_YET_RECRUITING

Marseille, France
Hôpital Privé de la Loire
ACTIVE_NOT_RECRUITING

Saint-Etienne, 42100, France
Hôpital privé Jean Mermoz
ACTIVE_NOT_RECRUITING

Lyon, 69373, France
Infirmerie Protestante de Lyon
ACTIVE_NOT_RECRUITING

Caluire-et-Cuire, France
Institut Bergonie
RECRUITING

Bordeaux, 33076, France
Institut Mutualiste Montsouris
RECRUITING

Paris, 75014, France
Institut de Cancerologie de Lorraine
NOT_YET_RECRUITING

Vandœuvre-lès-Nancy, France
Intitut Paoli Calmettes
RECRUITING

Marseille, France

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