New drug aims to stop immune attack after stem cell transplants

NCT ID NCT07246031

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called BPC2001 to prevent acute graft-versus-host disease (aGVHD), a serious complication where donor immune cells attack the patient's body after a stem cell transplant. Fifty adults with blood cancers like leukemia will receive six weekly doses of BPC2001 along with standard care. The goal is to see if the drug reduces the risk of aGVHD and is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BPC2001 (also known as KRN-7000)

What this could lead to

If it works, this could point toward a new way to prevent a serious complication of stem cell transplants, making the procedure safer for more patients.

What could go wrong

This is an early phase 2b trial with only 50 participants, so results may not apply to everyone. The drug could cause side effects or fail to reduce graft-versus-host disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute leukemia chronic graft versus host disease chronic myelomonocytic leukemia graft versus host disease myelodysplastic syndrome myeloproliferative neoplasm acute graft versus host disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••