Can botox shots warm up cold fingers? a trial investigates
NCT ID NCT05125029
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial tests whether injecting botulinum toxin into the fingers can improve blood flow and temperature in people with Raynaud's phenomenon that has not responded to standard treatments. Participants are randomly assigned to receive a placebo, a low dose, or a higher dose of the toxin. The study measures changes in finger temperature and oxygen levels, along with daily symptom ratings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- botulinum toxin injections into the fingers
- What this could lead to
- If it works, this could offer a new option for people with severe Raynaud's that does not respond to standard medications.
- What could go wrong
- This is a small, early-phase trial with only 24 participants. The effects may be modest, and injections carry risks like pain, infection, or temporary muscle weakness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RAYNAUD PHENOMENON are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Emory University Hospital
Atlanta, Georgia, 30322, United States