Botox injection may ease stubborn buttock and leg pain
NCT ID NCT07624045
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether injecting botulinum toxin (like Botox) into the piriformis muscle can reduce pain and improve quality of life in people with piriformis muscle syndrome. About 108 adults who have had buttock or leg pain for at least 3 months and haven't gotten relief from physical therapy or painkillers will receive either the toxin or a placebo. The goal is to see if this treatment offers a less invasive option before considering surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Besançon
Besançon, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Bordeaux
Bordeaux, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Nantes
Nantes, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Toulouse
Toulouse, France
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Centre Hospitalier Universitaire de Nîmes
Nîmes, Gard, 30029, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Universitaire Paris Cochin
Paris, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Universitaire de Réadaptation Clémenceau
Strasbourg, France
Contact Phone: •••-•••-•••• Email: •••••@•••••