Botox injection may ease stubborn buttock and leg pain

NCT ID NCT07624045

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting botulinum toxin (like Botox) into the piriformis muscle can reduce pain and improve quality of life in people with piriformis muscle syndrome. About 108 adults who have had buttock or leg pain for at least 3 months and haven't gotten relief from physical therapy or painkillers will receive either the toxin or a placebo. The goal is to see if this treatment offers a less invasive option before considering surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Besançon

    Besançon, France

  • CHU de Bordeaux

    Bordeaux, France

  • CHU de Nantes

    Nantes, France

  • CHU de Toulouse

    Toulouse, France

  • Centre Hospitalier Universitaire de Nîmes

    Nîmes, Gard, 30029, France

  • Hôpital Universitaire Paris Cochin

    Paris, France

  • Institut Universitaire de Réadaptation Clémenceau

    Strasbourg, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.