Botox or surgery? new study tests best way to prevent stomach issues after esophageal cancer surgery

NCT ID NCT06721520

First seen Feb 27, 2026 · Last updated May 04, 2026 · Updated 9 times

Summary

This study compares two methods to help the stomach empty properly after the esophagus is removed (esophagectomy) for cancer or other diseases. One method uses Botox injections into the stomach valve, the other is a surgical cut (pyloromyotomy). The goal is to see if Botox works as well as surgery to reduce symptoms like bloating and nausea. About 170 adults having planned esophagus removal will take part and report their symptoms for up to 2 years.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.