Botox for stress? tiny study tests the idea

NCT ID NCT06778421

Completed Symptom relief Sponsor: Center for Advanced Facial Plastic Surgery Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested whether Botox injections could lower stress levels in healthy adult women. Four participants received either Botox or a placebo (salt water) and filled out stress questionnaires over 12 weeks. The goal was to see if stress scores dropped after treatment. Because the study is very small and early, results are not conclusive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: OnabotulinumtoxinA (Botox)
What this could lead to: If it works, this could point toward a new way to ease stress using Botox injections.
What could go wrong: This is a very small, early pilot study with only 4 participants. Results may not apply to the general population, and the effect on stress is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Facial Expression Fractures, Stress Stress, Psychological

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY ADULT FEMALE PARTICIPANTS STRESS STRESS (PSYCHOLOGY) STRESS LEVELS STRESS PERCEPTION STRESS RESPONSE STRESS, PHYSIOLOGICAL STRESS, PSYCHOLOGIC STRESS, PSYCHOLOGICAL CUMULATIVE

Contacts and locations

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Locations

Center for Advanced Facial Plastic Surgery

Beverly Hills, California, 90212-2913, United States

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