Could botox calm the brain and cut seizures?
NCT ID NCT05605756
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study investigates whether Botox injections can lower seizure frequency and severity in adults with drug-resistant focal epilepsy. Researchers will measure changes in brain excitability and quality of life after treatment. The approach is based on shared features between epilepsy and migraine, which often respond to similar therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
OnabotulinumtoxinA (Botox)
What this could lead to
If it works, this could point toward a new treatment option for people with drug-resistant focal seizures.
What could go wrong
This is a very small early-phase trial with only 3 participants, so results may not apply broadly. Botox injections carry risks like muscle weakness or allergic reaction.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States