Could botox calm the brain and cut seizures?
NCT ID NCT05605756
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study investigates whether Botox injections can lower seizure frequency and severity in adults with drug-resistant focal epilepsy. Researchers will measure changes in brain excitability and quality of life after treatment. The approach is based on shared features between epilepsy and migraine, which often respond to similar therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- OnabotulinumtoxinA (Botox)
- What this could lead to
- If it works, this could point toward a new treatment option for people with drug-resistant focal seizures.
- What could go wrong
- This is a very small early-phase trial with only 3 participants, so results may not apply broadly. Botox injections carry risks like muscle weakness or allergic reaction.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States