Botox may help runners avoid surgery for leg pain
NCT ID NCT05466539
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether Botox injections could treat chronic leg pain in runners, a condition called chronic exertional compartment syndrome (CECS). Only 3 people took part, and they received Botox in specific leg muscles. The goal was to see if this could replace surgery, which is the current standard treatment. Because the study was very small, the results are not conclusive.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
abobotulinumtoxinA (Botox)
What this could lead to
If it works, this could offer a non-surgical treatment for chronic leg pain in runners, reducing recovery time.
What could go wrong
This was a very small, early-phase trial with only 3 participants, so results may not apply to everyone. The treatment is not yet proven effective.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Emory Hawks Sports Medicine Center
Brookhaven, Georgia, 30329, United States
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Emory Sports Medicine-Dunwoody
Atlanta, Georgia, 30338, United States