Facial workouts after botox: do they boost wrinkle smoothing?
NCT ID NCT01688076
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study looks at whether purposely contracting forehead muscles after Botox injections changes how quickly the treatment works, how well it reduces wrinkles, and how long the effect lasts. Researchers will inject Botox into the foreheads of 25 healthy adults aged 18–65 who already plan to get the treatment. Participants will be photographed over several months, and a dermatologist will rate wrinkle severity without knowing when each photo was taken. The goal is to see if muscle movement can improve cosmetic outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botulinum Toxin A (Botox)
- What this could lead to
- If muscle contraction speeds up or extends Botox's effects, people may get better wrinkle results from the same injection.
- What could go wrong
- This is a small, early-phase study with only 25 people. Results may not apply to everyone, and side effects like bruising or drooping are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Northwestern University Feinberg School of Medicine, Department of Dermatology
Chicago, Illinois, 60611, United States