Facial workouts after botox: do they boost wrinkle smoothing?
NCT ID NCT01688076
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study looks at whether purposely contracting forehead muscles after Botox injections changes how quickly the treatment works, how well it reduces wrinkles, and how long the effect lasts. Researchers will inject Botox into the foreheads of 25 healthy adults aged 18–65 who already plan to get the treatment. Participants will be photographed over several months, and a dermatologist will rate wrinkle severity without knowing when each photo was taken. The goal is to see if muscle movement can improve cosmetic outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Botulinum Toxin A (Botox)
What this could lead to
If muscle contraction speeds up or extends Botox's effects, people may get better wrinkle results from the same injection.
What could go wrong
This is a small, early-phase study with only 25 people. Results may not apply to everyone, and side effects like bruising or drooping are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Northwestern University Feinberg School of Medicine, Department of Dermatology
Chicago, Illinois, 60611, United States