Botox study targets wrinkles in japan – phase 3 complete

NCT ID NCT06794866

Completed Symptom relief Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested Botox (onabotulinumtoxinA) in 150 Japanese adults with moderate to severe forehead lines. Participants received injections of either Botox or a placebo and were followed for up to 12 months. The goal was to see if Botox safely reduces wrinkle severity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: OnabotulinumtoxinA (Botox)
What this could lead to: If it works, this could provide a safe and effective option for reducing forehead wrinkles in Japanese adults.
What could go wrong: This is a completed Phase 3 trial, but results are not yet published. Placebo group means some may not benefit, and side effects like bruising or temporary muscle weakness are possible.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FOREHEAD LINES

Contacts and locations

Locations

Akihabara Skin Clinic /ID# 268441

Tokyo, 101-0021, Japan
Chiharu Dermatology Clinic Urawa /ID# 268497

Saitama, 333-0055, Japan
Forest Palace Dermatology Clinic /ID# 268599

Nerima-ku, Tokyo, 177-0041, Japan
Ginza Skin Clinic /ID# 268532

Chuo-ku, Tokyo, 104-0061, Japan
Greenwood Skin Clinic Tachikawa /ID# 268528

Tachikawa-shi, Tokyo, 190-0023, Japan
Hiroshima Station Clinic /ID# 268467

Hiroshima, Hiroshima, 732-0053, Japan
Jun Clinic /ID# 268531

Nagano, Nagano, 380-0826, Japan
Kitasato University Kitasato Institute Hospital /ID# 268499

Minato-ku, Tokyo, 108-8642, Japan
Kotoni Tower Skin And Cosmetic Surgery Clinic /ID# 268460

Sapporo, Hokkaido, 063-0812, Japan
Queens Square Medical Center, Dermatology and Allergology /ID# 268454

Yokohama, Kanagawa, 220-6208, Japan
Tokai University Hospital /ID# 268496

Isehara, Kanagawa, 259-1193, Japan
Tokyo Asbo Clinic /ID# 268529

Chuo-ku, Tokyo, 104-0031, Japan
Tokyo Center Clinic /ID# 268477

Chuo-ku, Tokyo, 103-0027, Japan
Touyama Plastic Surgery Clinic /ID# 268456

Naha, Okinawa, 900-0015, Japan
Yoshikawa Skin Clinic /ID# 268494

Takatsuki, Osaka, 569-0824, Japan

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