Botox study targets wrinkles in japan – phase 3 complete

NCT ID NCT06794866

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested Botox (onabotulinumtoxinA) in 150 Japanese adults with moderate to severe forehead lines. Participants received injections of either Botox or a placebo and were followed for up to 12 months. The goal was to see if Botox safely reduces wrinkle severity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

OnabotulinumtoxinA (Botox)

What this could lead to

If it works, this could provide a safe and effective option for reducing forehead wrinkles in Japanese adults.

What could go wrong

This is a completed Phase 3 trial, but results are not yet published. Placebo group means some may not benefit, and side effects like bruising or temporary muscle weakness are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Akihabara Skin Clinic /ID# 268441

    Tokyo, 101-0021, Japan

  • Chiharu Dermatology Clinic Urawa /ID# 268497

    Saitama, 333-0055, Japan

  • Forest Palace Dermatology Clinic /ID# 268599

    Nerima-ku, Tokyo, 177-0041, Japan

  • Ginza Skin Clinic /ID# 268532

    Chuo-ku, Tokyo, 104-0061, Japan

  • Greenwood Skin Clinic Tachikawa /ID# 268528

    Tachikawa-shi, Tokyo, 190-0023, Japan

  • Hiroshima Station Clinic /ID# 268467

    Hiroshima, Hiroshima, 732-0053, Japan

  • Jun Clinic /ID# 268531

    Nagano, Nagano, 380-0826, Japan

  • Kitasato University Kitasato Institute Hospital /ID# 268499

    Minato-ku, Tokyo, 108-8642, Japan

  • Kotoni Tower Skin And Cosmetic Surgery Clinic /ID# 268460

    Sapporo, Hokkaido, 063-0812, Japan

  • Queens Square Medical Center, Dermatology and Allergology /ID# 268454

    Yokohama, Kanagawa, 220-6208, Japan

  • Tokai University Hospital /ID# 268496

    Isehara, Kanagawa, 259-1193, Japan

  • Tokyo Asbo Clinic /ID# 268529

    Chuo-ku, Tokyo, 104-0031, Japan

  • Tokyo Center Clinic /ID# 268477

    Chuo-ku, Tokyo, 103-0027, Japan

  • Touyama Plastic Surgery Clinic /ID# 268456

    Naha, Okinawa, 900-0015, Japan

  • Yoshikawa Skin Clinic /ID# 268494

    Takatsuki, Osaka, 569-0824, Japan