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New hope for hard-to-treat colorectal cancer? drug combo and radiation tested in small study

NCT ID NCT07128355

Recruiting now Disease control Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jan 26, 2026 · Last updated May 16, 2026 · Updated 14 times

Summary

This early-phase study tests whether combining two immunotherapy drugs (botensilimab and balstilimab) with targeted radiation can help people with a specific type of colorectal cancer that has spread to the liver and hasn't responded to standard treatments. The study will include 15 participants and primarily looks at safety and side effects. It aims to find a new way to control the disease when other options have failed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

NON-MSI-H OR PMMR COLORECTAL CANCER WITH LIVER METASTASIS