New drug cocktail aims to stop kidney rejection in transplant patients

NCT ID NCT02201576

First seen Feb 15, 2026 · Last updated May 31, 2026 · Updated 16 times

Summary

This study tested whether a drug called bortezomib, given with steroids, plasma exchange, and immunoglobulins, can treat chronic antibody-mediated rejection in kidney transplant recipients. The trial included 60 adults who had a kidney transplant and developed donor-specific antibodies. The goal was to see if this combination could reduce signs of rejection in kidney tissue and lower harmful antibody levels.

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Contacts and locations

Locations

  • Hopital Necker Enfants-malades

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.