New combo therapy targets stubborn kidney transplant rejection

NCT ID NCT02201576

First seen Feb 15, 2026 · Last updated Apr 28, 2026 · Updated 8 times

Summary

This study tested whether adding bortezomib to standard treatments (steroids, plasma exchange, and immunoglobulins) can help control chronic antibody-mediated rejection in kidney transplant recipients. 60 adults who had a kidney transplant and developed donor-specific antibodies were enrolled. The goal was to reduce signs of rejection in kidney biopsies and lower harmful antibody levels.

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Contacts and locations

Locations

  • Hopital Necker Enfants-malades

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.