Synthetic bone patch could rebuild noses without extra surgery

NCT ID NCT01234415

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a man-made bone material to repair the nasal septum in people with severe nose injuries from trauma. 26 adults received the material during rhinoplasty. The goal was to see if it is safe and effective at supporting the nose and helping the lining grow back, potentially avoiding the need to take bone from elsewhere in the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
synthetic bone material (HAP/TCP, BCP, Kasios®)
What this could lead to
If successful, this could offer a safer, simpler way to reconstruct the nose after severe injury, avoiding the need for a second surgical site to harvest bone.
What could go wrong
This is a small, early-phase trial with only 26 participants, so results may not apply to everyone. Risks include infection, material extrusion, and chronic inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service d'Oto-rhino-laryngologie - Clinique St Augustin

    Bordeaux, 33074, France

  • Service d'Oto-rhino-laryngologie - Hôpital Dupuytren

    Limoges, 87042, France

  • Service d'Oto-rhino-laryngologie et Chirurgie cervico-faciale - CHU de Bordeaux

    Bordeaux, 330176, France