New combo therapy aims to knock out bone metastasis pain
NCT ID NCT06859801
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is looking at whether combining two treatments — a minimally invasive procedure called percutaneous ablation and standard radiation therapy — can better relieve pain from bone cancer that has spread. Researchers will follow 120 people whose pain is not controlled by medication alone. The goal is to see how well the combo works in real-world settings, measuring pain levels, quality of life, and whether it reduces the need for hospital visits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Percutaneous ablation (a minimally invasive procedure using heat or cold to destroy nerve and tumor tissue) and palliative radiation therapy (targeted X-rays to shrink tumors and relieve pain)
- What this could lead to
- If successful, this combination approach could become a standard way to better control pain and reduce complications from bone metastases, improving quality of life for people with advanced cancer.
- What could go wrong
- This is an observational study, not a controlled experiment, so it cannot prove cause and effect. Results may vary widely among patients, and the procedures carry risks like infection, bleeding, or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Baptist Health Medical Group
RECRUITINGMiami, Florida, 33176, United States
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Emory University Hospital
RECRUITINGAtlanta, Georgia, 30322, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Northside Hospital
RECRUITINGAtlanta, Georgia, 30342, United States
Contact Email: •••••@•••••
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University of California San Diego Moores Cancer Center
RECRUITINGSan Diego, California, 92093, United States
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
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