Blue light could spot bladder tumors white light misses
NCT ID NCT02660645
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This registry study is gathering information on how well blue light cystoscopy with Cysview detects bladder cancer compared to standard white light cystoscopy. About 4400 adults with suspected or known non-muscle invasive bladder cancer will take part. The goal is to see if the blue light technique finds more tumors and helps guide more complete removal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hexaminolevulinate hydrochloride (Cysview) instilled in the bladder, used with a blue light cystoscopy device
- What this could lead to
- If successful, this could confirm that blue light cystoscopy with Cysview finds more bladder tumors than standard white light cystoscopy, leading to better detection and treatment.
- What could go wrong
- This is an observational registry, not a controlled trial, so results may not prove cause and effect. False positives could lead to unnecessary biopsies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Charleston Area Medical Center
TERMINATEDCharleston, West Virginia, 25301, United States
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Emory University School of Medicine
RECRUITINGAtlanta, Georgia, 30097, United States
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Indiana University School of Medicine
RECRUITINGIndianapolis, Indiana, 46202, United States
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Johns Hopkins Medicine
RECRUITINGBaltimore, Maryland, 21224, United States
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Lexington Medical Center
RECRUITINGWest Columbia, South Carolina, 29169, United States
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Mayo Clinic
RECRUITINGPhoenix, Arizona, 85054, United States
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Michael E. DeBakey VA Medical Center
RECRUITINGHouston, Texas, 77030, United States
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NYU Langone's Perlmutter Cancer Center
RECRUITINGNew York, New York, 10016, United States
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Northshore University Health System
RECRUITINGEvanston, Illinois, 60201, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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Ohio State University Wexner Medical Center
RECRUITINGColumbus, Ohio, 43210, United States
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Sibley Memorial Hospital
RECRUITINGWashington D.C., District of Columbia, 20016, United States
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Stony Brook Urology
SUSPENDEDStony Brook, New York, 11794, United States
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The University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
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USC/Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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UT Southwestern
RECRUITINGDallas, Texas, 75390, United States
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University of California Los Angeles
RECRUITINGLos Angeles, California, 90095, United States
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
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University of Washington Medicine
RECRUITINGSeattle, Washington, 98195, United States
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VA Palo Alto Health Care System
RECRUITINGPalo Alto, California, 94304, United States
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