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Blood test may replace needles for kids with kidney rejection

NCT ID NCT05477082

Knowledge-focused Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a blood test can help doctors know if treatment for kidney rejection is working in children who have had a kidney transplant. About 27 kids will give blood samples to check for special markers. The goal is to see if the blood test can predict and monitor rejection, possibly reducing the need for repeated kidney biopsies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

27 people

The number who actually took part.

Started

Aug 2023

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Pediatric kidney transplant recipients, ages \< 21 years, scheduled to undergo a for-cause kidney biopsy to rule out graft rejection

Ages

Up to 21 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Kidney transplant recipients * Participants undergoing a for-cause kidney biopsy to rule out graft rejection * Ages 21 years and less Exclusion Criteria: * Participants who have opted out of research * Patients, less than 18 years of age, whose parents or legal guardians are illiterate and cannot read. * Participants, 18 years and older, who are illiterate and cannot read. * Participants, less than 18 years of age, whose parents or legal guardians do not speak English. * Participants, 18 years and older, who do not speak English * Participants who are pregnant as confirmed by medical records

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Conditions

The condition(s) this trial relates to.

acute transplant rejection transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rejection of kidney allograft

Contacts and locations

Locations

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States