New blood test aims to detect colon cancer early

NCT ID NCT04792684

Recruiting now Diagnosis Sponsor: Universal Diagnostics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a blood test that looks for DNA fragments to detect colorectal cancer and advanced adenomas. Researchers will collect blood samples from 1,300 people in the U.S., including those with suspected cancer or adenomas and those undergoing routine screening. The goal is to improve the test's accuracy and potentially offer a simpler screening option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blood test (circulating free-DNA marker panel)
What this could lead to: If successful, this blood test could offer a simpler, less invasive way to screen for colorectal cancer and advanced adenomas, potentially catching them earlier.
What could go wrong: This is an observational study to optimize the test, not a treatment trial. The test may not be accurate enough to replace colonoscopy, and results are still being evaluated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal adenoma colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED ADENOMAS (AA) COLORECTAL CANCER (CRC)

Contacts and locations

Locations

Center for Gastrointestinal Disorders
COMPLETED

Hollywood, Florida, 33021, United States
Clinical Research of California
COMPLETED

Walnut Creek, California, 94598, United States
Clinical Trials Network
COMPLETED

Union City, Tennessee, 38261, United States
Dana Farber Cancer Institute
COMPLETED

Boston, Massachusetts, 02215, United States
Fox Chase Cancer Center
COMPLETED

Philadelphia, Pennsylvania, 19111, United States
Frontier Clinical Research
COMPLETED

Uniontown, Pennsylvania, 15401, United States
Gastroenterology Consultants of SW Virginia
COMPLETED

Raonoke, Virginia, 24014, United States
Lakeland Regional Cancer Center
RECRUITING

Lakeland, Florida, 33805, United States
Medical Associates Research Group
COMPLETED

San Diego, California, 92123, United States
Mid Hudson Medical Research
RECRUITING

New Windsor, New York, 12553, United States
Ochsner Clinic
COMPLETED

New Orleans, Louisiana, 70121, United States
Precision Recearch Institute
COMPLETED

Chula Vista, California, 91910, United States
Precision Research Institute
COMPLETED

San Diego, California, 92114, United States
Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Vilo Research Group
COMPLETED

Houston, Texas, 77017, United States

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