New blood test aims to detect colon cancer early

NCT ID NCT04792684

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a blood test that looks for DNA fragments to detect colorectal cancer and advanced adenomas. Researchers will collect blood samples from 1,300 people in the U.S., including those with suspected cancer or adenomas and those undergoing routine screening. The goal is to improve the test's accuracy and potentially offer a simpler screening option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

blood test (circulating free-DNA marker panel)

What this could lead to

If successful, this blood test could offer a simpler, less invasive way to screen for colorectal cancer and advanced adenomas, potentially catching them earlier.

What could go wrong

This is an observational study to optimize the test, not a treatment trial. The test may not be accurate enough to replace colonoscopy, and results are still being evaluated.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal adenoma colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Gastrointestinal Disorders

    COMPLETED

    Hollywood, Florida, 33021, United States

  • Clinical Research of California

    COMPLETED

    Walnut Creek, California, 94598, United States

  • Clinical Trials Network

    COMPLETED

    Union City, Tennessee, 38261, United States

  • Dana Farber Cancer Institute

    COMPLETED

    Boston, Massachusetts, 02215, United States

  • Fox Chase Cancer Center

    COMPLETED

    Philadelphia, Pennsylvania, 19111, United States

  • Frontier Clinical Research

    COMPLETED

    Uniontown, Pennsylvania, 15401, United States

  • Gastroenterology Consultants of SW Virginia

    COMPLETED

    Raonoke, Virginia, 24014, United States

  • Lakeland Regional Cancer Center

    RECRUITING

    Lakeland, Florida, 33805, United States

    Contact

  • Medical Associates Research Group

    COMPLETED

    San Diego, California, 92123, United States

  • Mid Hudson Medical Research

    RECRUITING

    New Windsor, New York, 12553, United States

    Contact

  • Ochsner Clinic

    COMPLETED

    New Orleans, Louisiana, 70121, United States

  • Precision Recearch Institute

    COMPLETED

    Chula Vista, California, 91910, United States

  • Precision Research Institute

    COMPLETED

    San Diego, California, 92114, United States

  • Springfield Clinic

    RECRUITING

    Springfield, Illinois, 62702, United States

    Contact

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

  • Vilo Research Group

    COMPLETED

    Houston, Texas, 77017, United States