Cuff-Limited exercise may boost blood health in anemic young women
NCT ID NCT07701213
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study investigates whether combining aerobic exercise with blood flow restriction—using a pressure cuff on the thigh—can improve key blood markers in young women with iron deficiency anemia. Fifty participants aged 19-25 with mild to moderate anemia will walk on a treadmill three times a week for three months while wearing the cuff. Researchers will measure changes in hemoglobin, ferritin, and other blood factors, as well as functional capacity and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise combined with blood flow restriction using a pressure cuff
- What this could lead to
- If effective, this approach could offer a non-drug way to improve anemia and quality of life in young women.
- What could go wrong
- This is a small, early-stage trial with only 50 participants, so results may not apply broadly. The blood flow restriction technique carries risks like bruising or clotting in susceptible individuals.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 25 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Hb more than 8 and less than 12 in females. 2. Age: 19-25 year. 3. BMI ranging from 25 to 29.9 kg/m2. 4. No existing inflammatory conditions including rheumatoid arthritis disorders of the lower extremities. 5. Physical activity level less than 150 min per week Exclusion Criteria: 1. unstable hypertension, venous thromboembolism, hypercoagulable states, varicose veins, pregnancy, and hemophilia. 2. inherited or acquired red cell disorders (haemoglobinopathies). 3. acute or chronic infections (malaria, tuberculosis, HIV),. 4. severe anemia (Hb \<8 g/dL). 5. History of cardiovascular diseases. 6. Nutritional anemia (B12/folate) 7. Pregnancy. 8. Peripheral arterial disease. 9. Intermittent claudication. 10. Non smokers
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
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