New strategies battle dangerous transplant side effect in blood cancer patients

NCT ID NCT03970096

Summary

This study is for people with acute leukemia or myelodysplastic syndrome (MDS) who need a stem cell transplant from a donor. The main goal is to find the best way to reduce a serious complication called graft-versus-host disease (GVHD), where the donor's immune cells attack the patient's body. Researchers are comparing two different approaches: one that filters out certain immune cells from the donor's blood before the transplant, and another that uses a specific drug (cyclophosphamide) after the transplant to control the immune reaction.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Pittsburgh Cancer Institute (UPCI)

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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