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Can a sham brain stimulation fool the mind? new study tests blinding integrity

NCT ID NCT07706790

Knowledge-focused Sponsor: Soroka University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether a sham version of rotational field transcranial magnetic stimulation (rfTMS) can effectively mimic the real treatment in healthy volunteers. Participants receive either active or sham stimulation over the front of the brain, and then report which they think they received. The goal is to see if the sham condition is convincing enough to blind participants, which would improve the design of future deep brain stimulation trials.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
rotational field transcranial magnetic stimulation (rfTMS) delivered through a multi-channel deep coil system
What this could lead to
If successful, this blinding method could make future deep TMS trials more reliable, helping researchers better understand the true effects of brain stimulation.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not fully predict blinding success in patient populations or real treatment settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Sep 2025

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy adults aged 18-65 * Hebrew or English speakers * No neurological, psychiatric, or developmental disorders * No contraindications for TMS * Able to provide informed consent Exclusion Criteria: * History of seizure * Metal implants in the head or neck * Pacemakers or implanted stimulators * Pregnancy * Current psychoactive medication affecting seizure threshold * Any contraindication listed in standard TMS safety guidelines

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers

Contacts and locations

Locations

  • Soroke University Medical Center

    Beersheba, Israel

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