Tiny trial tracks leukemia Drug's journey through the body

NCT ID NCT07295951

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study with 10 adults with acute leukemia looks at how the body absorbs, breaks down, and gets rid of the drug bleximenib. Participants take a radioactive version of the drug so researchers can track it in urine and stool. The goal is to understand the drug's path through the body, not to treat the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bleximenib (JNJ-75276617)

What this could lead to

If successful, this study will help researchers understand how bleximenib moves through the body, which could guide future dosing and safety decisions for treating acute leukemia.

What could go wrong

This is a very small, early-phase study focused on drug metabolism, not on curing or treating leukemia. It involves a radioactive tracer, and the drug may not work or may cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute leukemia acute lymphoblastic leukemia acute myeloid leukemia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Christie NHS Foundation Trust Christie Hospital

    RECRUITING

    Manchester, M20 4BX, United Kingdom