Which blood thinner is safer? major trial pits rivaroxaban against apixaban

NCT ID NCT04642430

First seen Nov 17, 2025 · Last updated May 13, 2026 · Updated 18 times

Summary

This study compares two common blood thinners, rivaroxaban and apixaban, to see which causes less bleeding in people with atrial fibrillation (an irregular heartbeat). About 3,000 adults with newly diagnosed AF will be randomly assigned to one of the two drugs. The goal is to help doctors choose the safer option for preventing strokes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Quebec - Université Laval

    NOT_YET_RECRUITING

    Laval, Quebec, Canada

    Contact

    Contact Email: •••••@•••••

  • CISSS de l'Outaouais

    RECRUITING

    Gatineau, Quebec, J8T 4J3, Canada

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Ciusss Nim

    RECRUITING

    Montreal, Quebec, H3L 1K5, Canada

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Kingston General Hospital

    RECRUITING

    Kingston, Ontario, Canada

    Contact

  • QEII Health Science Centre

    RECRUITING

    Halifax, Nova Scotia, Canada

    Contact

  • The Ottawa Hospital - General Campus

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • University Ottawa Heart Institute

    RECRUITING

    Ottawa, Ontario, Canada

    Contact

  • Victoria Cardiac Arrhythmia Trials

    RECRUITING

    Victoria, British Columbia, V8Z 0B9, Canada

    Contact

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.