Drug trial aims to shield patients from harsh chemo side effects while fighting bladder cancer

NCT ID NCT04887831

Summary

This study tested if adding a drug called trilaciclib to standard first-line chemotherapy and immunotherapy could better control advanced bladder cancer. The goal was to see if trilaciclib could help patients live longer without their cancer worsening while also protecting their bone marrow from chemotherapy's damaging side effects. The trial enrolled 92 adults with untreated, advanced bladder cancer and was terminated early.

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Contacts and locations

Locations

  • ALTHAIA, Xarxa Assistencial Universitiria de Manresa

    Manresa, Barcelona, 08243, Spain

  • Beacon Cancer Center PLLC

    Coeur d'Alene, Idaho, 83814, United States

  • Centre Léon Bérard - Département d'oncologie médicale

    Lyon, 69373, France

  • Florida Cancer Specialists - North

    St. Petersburg, Florida, 33705, United States

  • Florida Cancer Specialists - South

    Fort Myers, Florida, 33901, United States

  • Fundación Instituto Valenciano de Oncología

    Valencia, 46009, Spain

  • H.U. V. de las Nieves

    Granada, 18014, Spain

  • High Technology Hospital MedCenter LTD

    Batumi, Adjara, 6010, Georgia

  • Hopitaux Universitaires de Strasbourg - Service Oncologie et Hématologie

    Strasbourg, Bas-Rhin, 67091, France

  • Hospital Clinic de Barcelona - Servicio de Oncología Médica

    Barcelona, 08036, Spain

  • Hospital Politecnic Universitari La Fe

    Valencia, 46026, Spain

  • Hospital Universitario Lucus Augusti

    Lugo, 27003, Spain

  • Hospital Universitario Puerta de Hierro Majadahonda

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario Vall d´Hebron

    Barcelona, 08035, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, 08041, Spain

  • Hôpital Européen Georges Pompidou - Service d'Oncologie Médicale

    Paris, 75015, France

  • Institut Bergonié - Oncologie Médicale et Pédiatrique

    Bordeaux, Gironde, 33076, France

  • Institut Català d'Oncologia-Hospital Universitari Germans Trias i Pujol

    Badalona, Barcelona, 08916, Spain

  • Institut de Cancérologie de Lorraine

    Vandœuvre-lès-Nancy, 54519, France

  • Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz - Rendeloint

    Szolnok, Jász-Nagykun-Szolnok, H-5000, Hungary

  • LTD "Multiprofile Clinic Consilium Medulla"

    Tbilisi, 186, Georgia

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • National Center of Urology Named after Laur Managadze

    Tbilisi, 0144, Georgia

  • New York Oncology Hematology, P.C.

    Albany, New York, 12206, United States

  • Northwest Cancer Specialists, P.C.

    Tigard, Oregon, 46241, United States

  • Országos Onkológiai Intézet

    Budapest, 1122, Hungary

  • Rocky Mountain Cancer Centers

    Littleton, Colorado, 80120, United States

  • Tennessee Oncology, PLLC

    Nashville, Tennessee, 37203, United States

  • The Harry and Jeanette Weinberg Cancer Institute

    Baltimore, Maryland, 21237, United States

  • The Oncology Institute of Hope and Innovation

    Whittier, California, 90603, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • Uzsoki Utcai Kórház

    Budapest, H-1145, Hungary

  • Valkyrie Clinical Trial

    Los Angeles, California, 90067, United States

  • Woodlands Medical Specialists

    Pensacola, Florida, 32503, United States

Conditions

Explore the condition pages connected to this study.