New Bladder-Saving combo could spare cancer patients major surgery

NCT ID NCT07061964

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a combination of radiation therapy and an immunotherapy drug (pembrolizumab) can help patients with muscle-invasive bladder cancer avoid having their bladder surgically removed. It is for patients whose tumors have shrunk significantly after initial chemotherapy. The main goal is to see if this approach can keep the bladder cancer-free and the bladder intact for at least three years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Asplundh Cancer Pavilion
RECRUITING

Willow Grove, Pennsylvania, 19090, United States

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Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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CTCA at Southeastern Regional Medical Center
RECRUITING

Newnan, Georgia, 30265, United States

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Camden Clark Medical Center
RECRUITING

Parkersburg, West Virginia, 26101, United States

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Cancer Care Center of O'Fallon
RECRUITING

O'Fallon, Illinois, 62269, United States

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Cancer Care Specialists of Illinois - Decatur
RECRUITING

Decatur, Illinois, 62526, United States

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Cancer Care and Hematology-Fort Collins
RECRUITING

Fort Collins, Colorado, 80528, United States

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Carle Cancer Center
RECRUITING

Urbana, Illinois, 61801, United States

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Carle Physician Group-Effingham
RECRUITING

Effingham, Illinois, 62401, United States

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Carle Physician Group-Mattoon/Charleston
RECRUITING

Mattoon, Illinois, 61938, United States

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Carle at The Riverfront
RECRUITING

Danville, Illinois, 61832, United States

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Cedars Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States

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Cedars-Sinai Cancer - Tarzana
RECRUITING

Tarzana, California, 91356, United States

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City of Hope Antelope Valley
RECRUITING

Lancaster, California, 93534, United States

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City of Hope Comprehensive Cancer Center
RECRUITING

Duarte, California, 91010, United States

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City of Hope Corona
RECRUITING

Corona, California, 92882, United States

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City of Hope South Pasadena
RECRUITING

South Pasadena, California, 91030, United States

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City of Hope Upland
RECRUITING

Upland, California, 91786, United States

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City of Hope at Irvine Lennar
RECRUITING

Irvine, California, 92618, United States

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Community Medical Center
SUSPENDED

Missoula, Montana, 59804, United States
Crossroads Cancer Center
SUSPENDED

Effingham, Illinois, 62401, United States
Dartmouth Cancer Center - North
RECRUITING

Saint Johnsbury, Vermont, 05819, United States

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Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
RECRUITING

Lebanon, New Hampshire, 03756, United States

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Decatur Memorial Hospital
RECRUITING

Decatur, Illinois, 62526, United States

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Fairview Southdale Hospital
RECRUITING

Edina, Minnesota, 55435, United States

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HSHS Saint Elizabeth's Hospital
RECRUITING

O'Fallon, Illinois, 62269, United States

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Hunterdon Medical Center
RECRUITING

Flemington, New Jersey, 08822, United States

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Illinois CancerCare - Washington
RECRUITING

Washington, Illinois, 61571, United States

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Illinois CancerCare-Bloomington
RECRUITING

Bloomington, Illinois, 61704, United States

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Illinois CancerCare-Canton
RECRUITING

Canton, Illinois, 61520, United States

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Illinois CancerCare-Carthage
RECRUITING

Carthage, Illinois, 62321, United States

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Illinois CancerCare-Dixon
SUSPENDED

Dixon, Illinois, 61021, United States
Illinois CancerCare-Eureka
RECRUITING

Eureka, Illinois, 61530, United States

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Illinois CancerCare-Galesburg
RECRUITING

Galesburg, Illinois, 61401, United States

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Illinois CancerCare-Kewanee Clinic
RECRUITING

Kewanee, Illinois, 61443, United States

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Illinois CancerCare-Macomb
RECRUITING

Macomb, Illinois, 61455, United States

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Illinois CancerCare-Ottawa Clinic
RECRUITING

Ottawa, Illinois, 61350, United States

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Illinois CancerCare-Pekin
RECRUITING

Pekin, Illinois, 61554, United States

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Illinois CancerCare-Peoria
RECRUITING

Peoria, Illinois, 61615, United States

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Illinois CancerCare-Peru
RECRUITING

Peru, Illinois, 61354, United States

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Illinois CancerCare-Princeton
RECRUITING

Princeton, Illinois, 61356, United States

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Iowa Methodist Medical Center
RECRUITING

Des Moines, Iowa, 50309, United States

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Kootenai Clinic Cancer Services - Post Falls
SUSPENDED

Post Falls, Idaho, 83854, United States
Kootenai Clinic Cancer Services - Sandpoint
SUSPENDED

Sandpoint, Idaho, 83864, United States
Kootenai Health - Coeur d'Alene
SUSPENDED

Coeur d'Alene, Idaho, 83814, United States
Los Angeles General Medical Center
RECRUITING

Los Angeles, California, 90033, United States

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Mary Greeley Medical Center
RECRUITING

Ames, Iowa, 50010, United States

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Mayo Clinic Hospital in Arizona
RECRUITING

Phoenix, Arizona, 85054, United States

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Mayo Clinic in Florida
RECRUITING

Jacksonville, Florida, 32224-9980, United States

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McFarland Clinic - Ames
RECRUITING

Ames, Iowa, 50010, United States

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McFarland Clinic - Boone
SUSPENDED

Boone, Iowa, 50036, United States
McFarland Clinic - Jefferson
SUSPENDED

Jefferson, Iowa, 50129, United States
McFarland Clinic - Marshalltown
SUSPENDED

Marshalltown, Iowa, 50158, United States
McFarland Clinic - Trinity Cancer Center
SUSPENDED

Fort Dodge, Iowa, 50501, United States
Medical Center of the Rockies
RECRUITING

Loveland, Colorado, 80538, United States

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Mercy Cancer Center-West Lakes
RECRUITING

Clive, Iowa, 50325, United States

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Mercy Medical Center - Des Moines
RECRUITING

Des Moines, Iowa, 50314, United States

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Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States

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Moffitt Cancer Center - McKinley Campus
RECRUITING

Tampa, Florida, 33612, United States

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Moffitt Cancer Center at SouthShore
RECRUITING

Ruskin, Florida, 33570, United States

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Moffitt Cancer Center at Wesley Chapel
RECRUITING

Wesley Chapel, Florida, 33544, United States

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Moffitt Cancer Center-International Plaza
RECRUITING

Tampa, Florida, 33607, United States

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NYP/Weill Cornell Medical Center
RECRUITING

New York, New York, 10065, United States

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NorthShore University HealthSystem-Evanston Hospital
RECRUITING

Evanston, Illinois, 60201, United States

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NorthShore University HealthSystem-Glenbrook Hospital
RECRUITING

Glenview, Illinois, 60026, United States

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NorthShore University HealthSystem-Highland Park Hospital
RECRUITING

Highland Park, Illinois, 60035, United States

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Northwestern Medicine Cancer Center Delnor
RECRUITING

Geneva, Illinois, 60134, United States

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Northwestern Medicine Cancer Center Kishwaukee
RECRUITING

DeKalb, Illinois, 60115, United States

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Northwestern Medicine Cancer Center Warrenville
RECRUITING

Warrenville, Illinois, 60555, United States

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Northwestern Medicine Glenview Outpatient Center
RECRUITING

Glenview, Illinois, 60026, United States

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Northwestern Medicine Grayslake Outpatient Center
RECRUITING

Grayslake, Illinois, 60030, United States

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Northwestern Medicine Lake Forest Hospital
RECRUITING

Lake Forest, Illinois, 60045, United States

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Northwestern Medicine Oak Brook
RECRUITING

Oak Brook, Illinois, 60523, United States

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Northwestern Medicine Orland Park
RECRUITING

Orland Park, Illinois, 60462, United States

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Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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OSF Saint Francis Medical Center
RECRUITING

Peoria, Illinois, 61637, United States

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OSF Saint Francis Radiation Oncology at Peoria Cancer Center
RECRUITING

Peoria, Illinois, 61615, United States

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OSF Saint Joseph Medical Center
RECRUITING

Bloomington, Illinois, 61701, United States

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Park Nicollet Clinic - Saint Louis Park
RECRUITING

Saint Louis Park, Minnesota, 55416, United States

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Parkland Memorial Hospital
RECRUITING

Dallas, Texas, 75235, United States

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Poudre Valley Hospital
RECRUITING

Fort Collins, Colorado, 80524, United States

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Rush-Copley Medical Center
RECRUITING

Aurora, Illinois, 60504, United States

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Saint Francis Medical Center
RECRUITING

Cape Girardeau, Missouri, 63703, United States

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Saint Vincent Hospital Cancer Center Green Bay
RECRUITING

Green Bay, Wisconsin, 54301, United States

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Saint Vincent Hospital Cancer Center at Oconto Falls
RECRUITING

Oconto Falls, Wisconsin, 54154, United States

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Saint Vincent Hospital Cancer Center at Saint Mary's
RECRUITING

Green Bay, Wisconsin, 54303, United States

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Saint Vincent Hospital Cancer Center at Sheboygan
RECRUITING

Sheboygan, Wisconsin, 53081, United States

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Saint Vincent Hospital Cancer Center at Sturgeon Bay
RECRUITING

Sturgeon Bay, Wisconsin, 54235-1495, United States

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Sanford Broadway Medical Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford Cancer Center Oncology Clinic
RECRUITING

Sioux Falls, South Dakota, 57104, United States

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Sanford Joe Lueken Cancer Center
RECRUITING

Bemidji, Minnesota, 56601, United States

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Sanford Roger Maris Cancer Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford USD Medical Center - Sioux Falls
RECRUITING

Sioux Falls, South Dakota, 57117-5134, United States

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Shaw Cancer Center
RECRUITING

Edwards, Colorado, 81632, United States

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Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Memorial Hospital
RECRUITING

Springfield, Illinois, 62781, United States

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The Iowa Clinic PC
RECRUITING

West Des Moines, Iowa, 50266, United States

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The James Graham Brown Cancer Center at University of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States

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The New York Hospital Medical Center of Queens
RECRUITING

Flushing, New York, 11355, United States

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Thomas Jefferson University Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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Tower Cancer Research Foundation
RECRUITING

Beverly Hills, California, 90211, United States

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UCHealth Greeley Hospital
RECRUITING

Greeley, Colorado, 80631, United States

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UI Health Care Mission Cancer and Blood - Ankeny Clinic
RECRUITING

Ankeny, Iowa, 50023, United States

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UI Health Care Mission Cancer and Blood - Des Moines Clinic
RECRUITING

Des Moines, Iowa, 50309, United States

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UI Health Care Mission Cancer and Blood - Laurel Clinic
RECRUITING

Des Moines, Iowa, 50314, United States

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UI Health Care Mission Cancer and Blood - Waukee Clinic
RECRUITING

Waukee, Iowa, 50263, United States

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UI Health Care Mission Cancer and Blood - West Des Moines Clinic
RECRUITING

Clive, Iowa, 50325, United States

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USC / Norris Comprehensive Cancer Center
RECRUITING

Los Angeles, California, 90033, United States

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UT Southwestern Clinical Center at Richardson/Plano
RECRUITING

Richardson, Texas, 75080, United States

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UT Southwestern Simmons Cancer Center - RedBird
RECRUITING

Dallas, Texas, 75237, United States

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UT Southwestern/Simmons Cancer Center-Dallas
RECRUITING

Dallas, Texas, 75390, United States

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UT Southwestern/Simmons Cancer Center-Fort Worth
RECRUITING

Fort Worth, Texas, 76104, United States

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University Medical Center New Orleans
RECRUITING

New Orleans, Louisiana, 70112, United States

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University of Alabama at Birmingham Cancer Center
RECRUITING

Birmingham, Alabama, 35233, United States

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Contact Email: •••••@•••••
University of California Davis Comprehensive Cancer Center
RECRUITING

Sacramento, California, 95817, United States

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Contact Phone: •••-•••-••••
University of Cincinnati Cancer Center-UC Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States

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University of Cincinnati Cancer Center-West Chester
RECRUITING

West Chester, Ohio, 45069, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Kentucky/Markey Cancer Center
RECRUITING

Lexington, Kentucky, 40536, United States

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Contact Phone: •••-•••-••••
University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
UofL Health Medical Center Northeast
RECRUITING

Louisville, Kentucky, 40245, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
VCU Massey Cancer Center at Stony Point
RECRUITING

Richmond, Virginia, 23235, United States

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Contact Email: •••••@•••••
VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
West Virginia University Healthcare
RECRUITING

Morgantown, West Virginia, 26506, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

MUSCLE INVASIVE BLADDER UROTHELIAL CARCINOMA STAGE II BLADDER CANCER AJCC V8 STAGE IIIA BLADDER CANCER AJCC V8