New hope: immune drug may let some bladder cancer patients avoid bladder removal
NCT ID NCT05406713
First seen Apr 17, 2026 · Last updated May 14, 2026 · Updated 4 times
Summary
This study tests whether the immunotherapy drug pembrolizumab can shrink muscle-invasive bladder cancer enough to allow some patients to keep their bladder. About 46 adults with localized cancer will receive pembrolizumab, then be rechecked. If the cancer is gone or nearly gone, they continue on pembrolizumab and are watched closely. If not, they get standard treatment (like surgery or radiation) followed by more pembrolizumab. The goal is to see if this approach can safely spare the bladder while controlling the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope
Duarte, California, 91010, United States
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana, 46202, United States
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University of New Mexico Comprehensive Cancer Center
Albuquerque, New Mexico, 87102, United States
Conditions
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