Tiny Drug-Carrying particles aim to blast bladder cancer cells

This early-stage trial tests a new drug called PPM, which are tiny particles loaded with the chemotherapy drug paclitaxel and coated with a molecule (PLZ4) that helps them target bladder cancer cells. The drug is given directly into the bladder through a catheter once a week for six weeks. The study includes up to 29 people with non-muscle-invasive bladder cancer that has not responded to the standard BCG treatment. The main goals are to find the safest dose and to get an early look at whether the drug can shrink or eliminate the cancer.