Global trial aims to extend lives in advanced bladder cancer

NCT ID NCT03682068

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, global study is testing whether adding one or two immunotherapy drugs (durvalumab and tremelimumab) to standard chemotherapy works better than chemotherapy alone for people with advanced bladder cancer that cannot be removed by surgery. The main goal is to see if these combinations help patients live longer. Over 1,200 participants who have not had prior chemotherapy for their advanced disease are taking part.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Birmingham, Alabama, 35294, United States
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Bakersfield, California, 93309, United States
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Fullerton, California, 92835, United States
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Los Angeles, California, 90095, United States
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Salinas, California, 93901, United States
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Santa Barbara, California, 93105, United States
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Truckee, California, 96161, United States
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New Haven, Connecticut, 06520, United States
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Washington D.C., District of Columbia, 20007, United States
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Orlando, Florida, 32806, United States
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Chicago, Illinois, 60611, United States
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Fort Wayne, Indiana, 46804, United States
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Kansas City, Kansas, 66160, United States
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Louisville, Kentucky, 40202, United States
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New Orleans, Louisiana, 70112, United States
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Grand Rapids, Michigan, 49503, United States
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Bozeman, Montana, 59715, United States
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New Hyde Park, New York, 11042, United States
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New York, New York, 10029, United States
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New York, New York, 10065, United States
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Rochester, New York, 14642, United States
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Germantown, Tennessee, 38138, United States
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Fort Worth, Texas, 76104, United States
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Ciudad de Buenos Aires, 1280, Argentina
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Ciudad de Buenos Aires, C1120AAT, Argentina
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Ciudad de Buenos Aires, C1419AHL, Argentina
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Ciudad de Buenos Aires, C1426ANZ, Argentina
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Rosario, S2000DEJ, Argentina
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Box Hill, 3128, Australia
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Elizabeth Vale, 5112, Australia
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Kogarah, 2217, Australia
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Macquarie University, 2109, Australia
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Murdoch, 6150, Australia
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Orange, 2800, Australia
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South Brisbane, 4101, Australia
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St Albans, 3021, Australia
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Curitiba, 80810-050, Brazil
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Fortaleza, 60336-232, Brazil
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Porto Alegre, 90020-090, Brazil
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Porto Alegre, 90610-000, Brazil
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Porto Alegre, 91350-200, Brazil
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Ribeirão Preto, 14048-900, Brazil
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Rio de Janeiro, 20231-050, Brazil
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Rio de Janeiro, 22793-080, Brazil
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Salvador, 41.950-610, Brazil
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Santa Maria, 97015-450, Brazil
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São José do Rio Preto, 15090-000, Brazil
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São Paulo, 01246-000, Brazil
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São Paulo, 01327-001, Brazil
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Pleven, 5800, Bulgaria
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Plovdiv, 4000, Bulgaria
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Sofia, 1303, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 1527, Bulgaria
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Sofia, 1797, Bulgaria
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Varna, 9010, Bulgaria
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Calgary, Alberta, T2N 5G2, Canada
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Edmonton, Alberta, T6G 1Z2, Canada
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Vancouver, British Columbia, V5Z 4E6, Canada
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Hamilton, Ontario, L8V 5C2, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Toronto, Ontario, M5G IX6, Canada
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Montreal, Quebec, H3T 1E2, Canada
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Beijing, 100034, China
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Beijing, 100191, China
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Beijing, 100730, China
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Changchun, 130021, China
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Changsha, 410008, China
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Changsha, 410013, China
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Chongqing, 400038, China
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Chongqing, 400042, China
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Dalian, 116027, China
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Guangzhou, 510000, China
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Guangzhou, 510060, China
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Hangzhou, 310003, China
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Hangzhou, 310009, China
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Hangzhou, 310014, China
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Hangzhou, 310022, China
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Jinan, 250012, China
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Nanchang, 330006, China
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Nanjing, 2100008, China
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Shanghai, 200032, China
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Shanghai, 200072, China
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Shenyang, 110001, China
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Suzhou, 215006, China
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Tianjin, 300211, China
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Tianjin, China
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Ürümqi, 830000, China
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Wuhan, 430022, China
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Xi'an, 710061, China
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Brno, 656 91, Czechia
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Hradec Králové, 500 05, Czechia
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Olomouc, 77900, Czechia
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Ostrava, 708 52, Czechia
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Prague, 128 08, Czechia
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Prague, 140 59, Czechia
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Prague, 180 81, Czechia
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Budapest, 1062, Hungary
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Budapest, 1122, Hungary
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Budapest, 1145, Hungary
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Debrecen, 4032, Hungary
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Győr, 9024, Hungary
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Kecskemét, 6000, Hungary
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Szolnok, 5000, Hungary
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Gūrgaon, 122001, India
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Hubli, 580025, India
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Kolkata, 700160, India
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Mysuru, 570017, India
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Nagpur, 440012, India
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Nashik, 422005, India
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New Delhi, 110085, India
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New Delhi, 11029, India
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Pune, 411004, India
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Haifa, 31096, Israel
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Jerusalem, 91120, Israel
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Kfar Saba, 95847, Israel
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Petah Tikva, 4941492, Israel
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Ramat Gan, 52621, Israel
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Arezzo, 52100, Italy
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Milan, 20132, Italy
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Milan, 20133, Italy
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Naples, 80131, Italy
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Orbassano, 10043, Italy
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Parma, 43126, Italy
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Pavia, 27100, Italy
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Roma, 00100, Italy
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Terni, 05100, Italy
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Verona, 37134, Italy
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Bunkyō City, 113-8603, Japan
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Chūōku, 104-0045, Japan
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Fukuoka, 811-1347, Japan
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Hirosaki-shi, 036-8563, Japan
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Kanazawa, 920-8641, Japan
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Kita-gun, 761-0793, Japan
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Koshigaya-shi, 343-8555, Japan
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Kōtoku, 135-8550, Japan
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Kumamoto, 860-0008, Japan
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Kumamoto, 860-8556, Japan
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Kyoto, 606-8507, Japan
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Miyazaki, 889-1692, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 466-8560, Japan
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Nagoya, 467-0001, Japan
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Niigata, 951-8520, Japan
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Osaka, 541-8567, Japan
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Osaka, 545-8586, Japan
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Osakasayama-shi, 589-8511, Japan
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Shinjuku-ku, 160-8582, Japan
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Suita-shi, 565-0871, Japan
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Toyama, 930-0194, Japan
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Yokohama, 232-0024, Japan
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Yokohama, 241-8515, Japan
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Bacolod, 6100, Philippines
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Baguio City, 2600, Philippines
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Cebu, 6000, Philippines
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Davao City, 8000, Philippines
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Makati, 1229, Philippines
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Manila, 1015, Philippines
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Quezon City, 1101, Philippines
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Quezon City, 1104, Philippines
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Bialystok, 15-027, Poland
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Gdansk, 80-952, Poland
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Grudziądz, 86-300, Poland
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Koszalin, 75-581, Poland
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Krakow, 31-501, Poland
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Olsztyn, 10-228, Poland
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Poznan, 60-693, Poland
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Radom, 26-600, Poland
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Warsaw, 02-781, Poland
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Ivanovo, 153040, Russia
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Krasnoyarsk, 660133, Russia
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Moscow, 105077, Russia
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Moscow, 105229, Russia
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Moscow, 115280, Russia
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Moscow, 125284, Russia
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Nizhny Novgorod, 603074, Russia
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Nizhny Novgorod, 603137, Russia
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Omsk, 644013, Russia
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Rostov-on-Don, 344037, Russia
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Saint Petersburg, 195067, Russia
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Saint Petersburg, 197758, Russia
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Saint Petersburg, 199178, Russia
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Tyumen, 625041, Russia
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Vologda, 160012, Russia
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Goyang-si, 10408, South Korea
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Incheon, 21565, South Korea
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Seoul, 02841, South Korea
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Seoul, 03722, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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Suwon, 16247, South Korea
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Barcelona, 08908, Spain
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Barcelona, 8003, Spain
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Barcelona, 8035, Spain
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Lugo, 27003, Spain
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Madrid, 28007, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Málaga, 29010, Spain
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Santander, 39008, Spain
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Seville, 41013, Spain
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Taichung, 404, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 704, Taiwan
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Taipei, 10050, Taiwan
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Taipei, 11217, Taiwan
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Taoyuan District, 333, Taiwan
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Bangkok, 10300, Thailand
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Bangkok, 10400, Thailand
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Khon Kaen, 40002, Thailand
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Mueang, 50200, Thailand
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Songkhla, 90110, Thailand
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Adana, 1260, Turkey (Türkiye)
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Adapazarı, 54290, Turkey (Türkiye)
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Ankara, 06590, Turkey (Türkiye)
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Edirne, 22030, Turkey (Türkiye)
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Istanbul, 34030, Turkey (Türkiye)
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Izmir, Turkey (Türkiye)
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Hanoi, 100000, Vietnam
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Hanoi, 10000, Vietnam
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Hà Nội, 100000, Vietnam
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Ho Chi Minh City, 70000, Vietnam

Conditions

Explore the condition pages connected to this study.

METASTATIC UROTHELIAL CANCER UNRESECTABLE LOCALLY ADVANCED UROTHELIAL CANCER