Major trial tests if adding immunotherapy can stop bladder Cancer's return

NCT ID NCT03528694

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, global study is testing whether adding a new immunotherapy drug called durvalumab to the standard BCG treatment works better than BCG alone for people with high-risk bladder cancer that hasn't spread into the muscle wall. The main goal is to see if the combination helps patients stay cancer-free for longer and prevents the cancer from becoming more invasive. Over 1,000 participants who haven't had BCG treatment recently are being randomly assigned to receive either the new combination or the standard treatment.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Auchenflower, 4066, Australia
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Box Hill, 3128, Australia
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Brisbane, 4122, Australia
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Kogarah, 2217, Australia
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Orange, 2800, Australia
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Parkville, 3000, Australia
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Westmead, 2145, Australia
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Wollongong, 2500, Australia
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Graz, 8036, Austria
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Innsbruck, 6020, Austria
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Linz, 4020, Austria
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Salzburg, 5020, Austria
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Vienna, 1090, Austria
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Brussels, 1070, Belgium
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Ghent, 9000, Belgium
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Leuven, 3000, Belgium
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Roeselare, 8800, Belgium
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Kingston, Ontario, K7L 3J7, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Chicoutimi, Quebec, G7H 5H6, Canada
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Montreal, Quebec, H2X 3E4, Canada
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Québec, Quebec, G1J 1Z4, Canada
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Amiens, 80054, France
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Angers, 49033, France
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Bordeaux, 33076, France
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Lyon, 69437, France
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Marseille, 13003, France
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Montpellier, 34295, France
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Strasbourg, 67200, France
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Suresnes, 92151, France
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Berlin, 10117, Germany
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Cologne, 50968, Germany
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Duisburg, 47169, Germany
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Hanover, 30625, Germany
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Heidelberg, 69120, Germany
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Marburg, 35043, Germany
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Mettmann, 40822, Germany
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Mühlheim An Der Ruhr, 45468, Germany
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München, 81377, Germany
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Münster, 48149, Germany
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Nürtingen, 72622, Germany
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Wesel, 46483, Germany
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Würselen, 52146, Germany
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Zirndorf, 90513, Germany
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Bunkyō City, 113-8603, Japan
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Fukuoka, 812-8582, Japan
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Hirosaki-shi, 036-8563, Japan
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Kanazawa, 920-8641, Japan
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Kita-gun, 761-0793, Japan
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Koshigaya-shi, 343-8555, Japan
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Kōtoku, 135-8550, Japan
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Matsuyama, 791-0280, Japan
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Miyazaki, 889-1692, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 467-0001, Japan
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Okayama, 700-8558, Japan
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Osaka, 541-8567, Japan
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Osaka, 545-8586, Japan
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Osakasayama-shi, 589-8511, Japan
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Sapporo, 060-8543, Japan
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Shinjuku-ku, 160-8582, Japan
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Toyama, 930-0194, Japan
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Tsukuba, 305-8576, Japan
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Yokohama, 232-0024, Japan
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Amsterdam, 1081 HV, Netherlands
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Breda, 4818 CK, Netherlands
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Utrecht, 3543 AZ, Netherlands
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Bialystok, 15-950, Poland
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Gdansk, 80-952, Poland
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Grudziądz, 86-300, Poland
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Koszalin, 75-581, Poland
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Piotrkow Trybunalski, 97-300, Poland
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Poznan, 61-731, Poland
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Warsaw, 02-005, Poland
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Warsaw, 02-781, Poland
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Wroclaw, 50-556, Poland
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Wroclaw, 53-413, Poland
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Ivanovo, 153040, Russia
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Krasnoyarsk, 660133, Russia
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Moscow, 105077, Russia
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Moscow, 115280, Russia
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Moscow, 125367, Russia
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Nizhny Novgorod, 603074, Russia
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Obninsk, 249036, Russia
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Omsk, 644013, Russia
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Saint Petersburg, 191014, Russia
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Saint Petersburg, 194017, Russia
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Saint Petersburg, 194044, Russia
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Saint Petersburg, 194354, Russia
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Saint Petersburg, 195271, Russia
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Saint Petersburg, 197758, Russia
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Vologda, 160012, Russia
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Yaroslavl, 150054, Russia
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Badajoz, 06008, Spain
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Barcelona, 08025, Spain
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Barcelona, 08036, Spain
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Barcelona, 08208, Spain
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Barcelona, 8003, Spain
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Elche(Alicante), 03202, Spain
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Madrid, 08035, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Madrid, 28046, Spain
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Málaga, 29010, Spain
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Oviedo, 33011, Spain
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Pamplona, 31008, Spain
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Pozuelo de Alarcón, 28223, Spain
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Seville, 41009, Spain
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Seville, 41014, Spain
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Valencia, 46014, Spain
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Valencia, 46026, Spain
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Birmingham, B15 2TH, United Kingdom
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Glasgow, G12 0YN, United Kingdom
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Guildford, CU2 7XX, United Kingdom
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London, E1 1BB, United Kingdom
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London, NW1 2PG, United Kingdom
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London, SE1 9RT, United Kingdom
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Sheffield, S10 2JF, United Kingdom
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Southampton, S016 6YD, United Kingdom
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Taunton, TA1 5DA, United Kingdom

Conditions

Explore the condition pages connected to this study.

NON-MUSCLE-INVASIVE BLADDER CANCER