New hope for bladder cancer patients who Can't take standard chemo

NCT ID NCT04960709

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This global study is testing whether adding new immunotherapy and targeted drugs to the treatment plan around bladder removal surgery works better than current standard care. It's for patients with muscle-invasive bladder cancer who are not eligible for or refuse the usual cisplatin chemotherapy. About 712 participants will be randomly assigned to receive either the new drug combinations or standard treatment before and after their surgery.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Orange, California, 92868, United States
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Santa Monica, California, 90404, United States
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New Haven, Connecticut, 06510, United States
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Washington D.C., District of Columbia, 20010, United States
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Fort Myers, Florida, 33901, United States
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Coeur d'Alene, Idaho, 83814, United States
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Maywood, Illinois, 60153, United States
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Indianapolis, Indiana, 46250, United States
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Iowa City, Iowa, 52242, United States
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Louisville, Kentucky, 40207, United States
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Scarborough, Maine, 04074, United States
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Boston, Massachusetts, 02111, United States
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Brighton, Michigan, 48114, United States
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Jackson, Mississippi, 39213, United States
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Las Vegas, Nevada, 89102, United States
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Saddle Brook, New Jersey, 07663, United States
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Brooklyn, New York, 11219, United States
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Buffalo, New York, 14263, United States
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New York, New York, 10040, United States
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Syracuse, New York, 13210, United States
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Portland, Oregon, 97239, United States
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Hershey, Pennsylvania, 17033, United States
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Pittsburgh, Pennsylvania, 15212, United States
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Knoxville, Tennessee, 37932, United States
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Austin, Texas, 78731, United States
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Dallas, Texas, 75246, United States
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Fort Worth, Texas, 76104, United States
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Houston, Texas, 77030, United States
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Irving, Texas, 75063, United States
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Norfolk, Virginia, 23502, United States
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Spokane, Washington, 99208, United States
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Buenos Aires, C1431FWO, Argentina
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CABA, C1426ANZ, Argentina
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Ciudad de Buenos Aires, C1280AEB, Argentina
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Ciudad de Buenos Aires, C1419AHL, Argentina
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Pergamino, B2700CPM, Argentina
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Pilar, B1629AHJ, Argentina
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Graz, 8036, Austria
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Krems, 3500, Austria
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Linz, 4020, Austria
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Salzburg, 5020, Austria
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Vienna, 1020, Austria
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Vienna, 1090, Austria
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Wiener Neustadt, 2700, Austria
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Barretos, 14784-400, Brazil
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Curitiba, 81520-060, Brazil
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Fortaleza, 60135-237, Brazil
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Porto Alegre, 90035-001, Brazil
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Porto Alegre, 90035-003, Brazil
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Porto Alegre, 90610-000, Brazil
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Porto Alegre, 91350200, Brazil
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Rio de Janeiro, 22250-905, Brazil
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Santa Maria, 97015-450, Brazil
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Santo André, 09060-650, Brazil
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São Paulo, 01246-000, Brazil
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São Paulo, 01323-903, Brazil
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Săo Paulo, 03162-065, Brazil
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Uberlândia, 38408-150, Brazil
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Abbotsford British Columbia, British Columbia, V2S 3N5, Canada
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Toronto, Ontario, M4N 3M5, Canada
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Québec, Quebec, G1R 2J6, Canada
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Sherbrooke, Quebec, J1H 5N4, Canada
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Santiago, 7500653, Chile
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Santiago, 7500921, Chile
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Amiens, 80090, France
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Bayonne, 64100, France
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Clermont-Ferrand, 63011, France
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Lille, 59000, France
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Lyon, 69008, France
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Marseille, 13273, France
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Marseille, 13385, France
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Montpellier, 34070, France
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Nice, 06189, France
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Pierre-Bénite, 69495, France
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Quint-Fonsegrives, 31130, France
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Saint-Priez En Jarez, 42270, France
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Strasbourg, 67091, France
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Suresnes, 92151, France
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Vandœuvre-lès-Nancy, 54519, France
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Bielefeld, 33611, Germany
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Bochum, 44791, Germany
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Cologne, 50937, Germany
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Düsseldorf, 40225, Germany
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Giessen, 35392, Germany
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Hanover, 30625, Germany
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Herne, 44625, Germany
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Magdeburg, 39120, Germany
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Mainz, 55131, Germany
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Mannheim, 68167, Germany
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München, 81377, Germany
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Münster, 48149, Germany
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Regensburg, 93053, Germany
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Reutlingen, 72766, Germany
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Ulm, 89075, Germany
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Athens, 11528, Greece
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Athens, 12462, Greece
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Maroussi, Athens, 15125, Greece
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Shatin, 00000, Hong Kong
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Hadera, 38100, Israel
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Haifa, 31096, Israel
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Jerusalem, 9103102, Israel
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Jerusalem, 9112001, Israel
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Tel Aviv, 64239, Israel
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Bari, 70124, Italy
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Florence, 50134, Italy
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Meldola, 47014, Italy
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Milan, 20132, Italy
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Milan, 20141, Italy
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Padua, 35128, Italy
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Pozzuoli, 80078, Italy
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Reggio Emilia, 42100, Italy
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Roma, 00128, Italy
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Roma, 00137, Italy
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Roma, 00144, Italy
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Terni, 05100, Italy
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Tricase, 73039, Italy
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Verona, 37124, Italy
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Bunkyō City, 113-8431, Japan
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Fukuoka, 811-1395, Japan
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Hamamatsu, 431-3192, Japan
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Ichikawa-shi, 272-8516, Japan
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Kanazawa, 920-8641, Japan
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Kashihara-shi, 634-8522, Japan
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Kawasaki-shi, 216-8511, Japan
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Kita-gun, 761-0793, Japan
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Kobe, 650-0017, Japan
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Kumamoto, 860-0008, Japan
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Matsuyama, 791-0288, Japan
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Miyazaki, 889-1692, Japan
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Niigata, 951-8566, Japan
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Okayama, 700-8558, Japan
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Osaka, 541-8567, Japan
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Osaka, 545-8586, Japan
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Osakasayama-shi, 589-8511, Japan
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Toyama, 930-0194, Japan
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Tsukuba, 305-8576, Japan
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Yokohama, 241-8515, Japan
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Colima, 28018, Mexico
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Monterrey, 64000, Mexico
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Arnhem, 6815 AD, Netherlands
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Breda, 4818 CK, Netherlands
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Groningen, 9713 GZ, Netherlands
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Hoofddorp, 2134 TM, Netherlands
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Leiden, 2333 ZA, Netherlands
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Utrecht, 3508 GA, Netherlands
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Gdansk, 80-214, Poland
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Nowa Sól, 67-106, Poland
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Skórzewo, 60-185, Poland
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Warsaw, 02-781, Poland
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Braga, 4710, Portugal
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Coimbra, 3000-075, Portugal
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Faro, 8000-386, Portugal
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Lisbon, 1169-050, Portugal
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Lisbon, 1350-352, Portugal
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Lisbon, 1500-458, Portugal
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Lisbon, 1500-650, Portugal
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Lisbon, 1649-035, Portugal
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Belgrade, 11000, Serbia
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Kamenitz, 21204, Serbia
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Busan, 47392, South Korea
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Goyang-si, 10408, South Korea
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Incheon, 405-760, South Korea
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Seongnam-si, 13620, South Korea
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Seoul, 02841, South Korea
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Seoul, 03080, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Seoul, 07985, South Korea
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Barcelona, 08035, Spain
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Barcelona, 08036, Spain
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Barcelona, 08041, Spain
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Barcelona, 08208, Spain
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L'Hospitalet de Llobregat, 08907, Spain
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Las Palmas de Gran Canaria, 35016, Spain
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Madrid, 28033, Spain
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Madrid, 28040, Spain
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Madrid, 28046, Spain
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Pamplona, 31008, Spain
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Seville, 41009, Spain
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Taichung, 40447, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Tainan, 710, Taiwan
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Bangkok, 10330, Thailand
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Dusit, 10300, Thailand
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Songkhla, 90110, Thailand
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Adana, 01060, Turkey (Türkiye)
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Ankara, 06560, Turkey (Türkiye)
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Ankara, 06620, Turkey (Türkiye)
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Ankara, 5000, Turkey (Türkiye)
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Ankara, Turkey (Türkiye)
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Antalya, 07025, Turkey (Türkiye)
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Cordaleo, 35575, Turkey (Türkiye)
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Edirne, 22030, Turkey (Türkiye)
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Istanbul, 32098, Turkey (Türkiye)
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Istanbul, 34722, Turkey (Türkiye)
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London, EC1A 7BE, United Kingdom
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London, NW1 2PG, United Kingdom
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Hanoi, 100000, Vietnam
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Hà Nội, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Huế, 530000, Vietnam

Conditions

Explore the condition pages connected to this study.

MUSCLE INVASIVE BLADDER CANCER