Major global trial aims to stop bladder cancer from coming back

NCT ID NCT03732677

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large, global study is testing whether adding a newer immunotherapy drug (durvalumab) to standard chemotherapy before bladder removal surgery, and then continuing the immunotherapy alone after surgery, can better control cancer and prevent it from returning. It involves over 1,000 patients with muscle-invasive bladder cancer who are planning to have surgery. The main goals are to see if this approach leads to no detectable cancer at surgery and helps patients live longer without their cancer progressing.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Sherbrooke, Quebec, J1H 5N4, Canada
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Antofagasta, 1267348, Chile
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Port Montt, 5480000, Chile
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Santiago, 7520349, Chile
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Temuco, 4810218, Chile
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Temuco, 4810469, Chile
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Viña del Mar, 2540488, Chile
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Brno, 656 53, Czechia
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Brno, 656 91, Czechia
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Hradec Králové, 500 05, Czechia
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Olomouc, 77900, Czechia
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Prague, 128 08, Czechia
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Prague, 140 59, Czechia
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Prague, 180 81, Czechia
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Angers, 49033, France
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Dijon, 21079, France
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Grenoble, 38043, France
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Montpellier, 34070, France
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Nîmes, 30029, France
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Pierre-Bénite, 69495, France
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Poitiers, 86021, France
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Rouen, F-76031 CE, France
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Bergisch Gladbach, 51465, Germany
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Bonn, 53127, Germany
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Cologne, 50937, Germany
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Erlangen, 91054, Germany
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Göttingen, 37075, Germany
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Herne, 44625, Germany
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Jena, 07747, Germany
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Magdeburg, 39120, Germany
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Mannheim, 68167, Germany
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Münster, 48149, Germany
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Nuremberg, 90491, Germany
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Oldenburg, 23758, Germany
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Regensburg, 93053, Germany
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Ulm, 89081, Germany
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Würzburg, 97080, Germany
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Haifa, 31096, Israel
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Jerusalem, 91120, Israel
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Kfar Saba, 95847, Israel
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Petah Tikva, 4941492, Israel
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Ramat Gan, 52621, Israel
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Bari, 70124, Italy
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Bologna, 40138, Italy
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Florence, 50134, Italy
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Milan, 20132, Italy
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Milan, 20133, Italy
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Naples, 80131, Italy
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Orbassano, 10043, Italy
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Pozzuoli, 80078, Italy
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Verona, 37126, Italy
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Bunkyō City, 113-8603, Japan
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Fukuoka, 811-1347, Japan
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Fukuoka, 812-8582, Japan
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Hirosaki-shi, 036-8563, Japan
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Hiroshima, 730-8518, Japan
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Kanazawa, 920-8641, Japan
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Kōtoku, 135-8550, Japan
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Kumamoto, 860-0008, Japan
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Miyazaki, 889-1692, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 466-8560, Japan
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Niigata, 951-8520, Japan
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Osaka, 541-8567, Japan
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Osaka, 545-8586, Japan
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Osakasayama-shi, 589-8511, Japan
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Sendai, 980-0872, Japan
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Toyama, 930-0194, Japan
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Tsukuba, 305-8576, Japan
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Yokohama, 232-0024, Japan
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Yokohama, 241-8515, Japan
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Amsterdam, 1066 CX, Netherlands
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Amsterdam, 1081 HV, Netherlands
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Breda, 4818 CK, Netherlands
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Rotterdam, 3015 GD, Netherlands
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Baguio City, 2600, Philippines
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Cebu, 6000, Philippines
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Davao City, 8000, Philippines
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Makati, 1229, Philippines
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Manila, 1015, Philippines
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Quezon City, 1101, Philippines
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Quezon City, 1104, Philippines
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Bialystok, 15-027, Poland
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Gdansk, 80-952, Poland
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Grudziądz, 86-300, Poland
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Koszalin, 75-581, Poland
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Krakow, 30-510, Poland
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Olsztyn, 10-228, Poland
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Ostrołęka, 07-410, Poland
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Poznan, 60-693, Poland
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Warsaw, 02-781, Poland
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Wroclaw, 53-413, Poland
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Krasnoyarsk, 660133, Russia
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Moscow, 105077, Russia
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Nizhny Novgorod, 603074, Russia
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Novosibirsk, 630007, Russia
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Saint Petersburg, 194017, Russia
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Saint Petersburg, 194044, Russia
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Saint Petersburg, 194354, Russia
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Saint Petersburg, 197022, Russia
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Samara, 443031, Russia
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Ufa, 450000, Russia
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Vologda, 160012, Russia
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Daegu, 41404, South Korea
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Goyang-si, 10408, South Korea
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Gyeonggi-do, 13620, South Korea
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Incheon, 21565, South Korea
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Seoul, 03080, South Korea
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Seoul, 05505, South Korea
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Seoul, 136-705, South Korea
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Badalona, 08916, Spain
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Barcelona, 08035, Spain
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Córdoba, 14004, Spain
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Las Palmas de Gran Canaria, 35016, Spain
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Madrid, 28007, Spain
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Madrid, 28041, Spain
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Santander, 39008, Spain
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Seville, 41013, Spain
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Kaohsiung City, 807, Taiwan
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Taichung, 404, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 704, Taiwan
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Tainan, 710, Taiwan
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Taipei, 10050, Taiwan
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Taipei, 11217, Taiwan
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Taoyuan, 333, Taiwan
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Ankara, 06590, Turkey (Türkiye)
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Cordaleo, 35575, Turkey (Türkiye)
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Edirne, 22030, Turkey (Türkiye)
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Istanbul, 34030, Turkey (Türkiye)
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Istanbul, 34457, Turkey (Türkiye)
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Izmir, Turkey (Türkiye)
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Edinburgh, EH4 2XR, United Kingdom
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London, E1 1BB, United Kingdom
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Metropolitan Borough of Wirral, CH63 4JY, United Kingdom
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Nottingham, NG5 1PB, United Kingdom
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Sheffield, S10 2SJ, United Kingdom
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Hanoi, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Hochiminh, 70000, Vietnam
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Birmingham, Alabama, 35294, United States
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Los Angeles, California, 90095, United States
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Palo Alto, California, 94304, United States
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New Haven, Connecticut, 06520, United States
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Chicago, Illinois, 60611, United States
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Geneva, Illinois, 60134, United States
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Iowa City, Iowa, 52242, United States
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Westwood, Kansas, 66205, United States
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Louisville, Kentucky, 40202, United States
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New Orleans, Louisiana, 70112, United States
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Towson, Maryland, 21204, United States
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Ann Arbor, Michigan, 48109, United States
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Detroit, Michigan, 48201, United States
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New York, New York, 10029, United States
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Rochester, New York, 14642, United States
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Bethlehem, Pennsylvania, 18015, United States
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Burlington, Vermont, 05401, United States
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Milwaukee, Wisconsin, 53226, United States
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Brisbane, 4122, Australia
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Elizabeth Vale, 5112, Australia
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Macquarie University, 2109, Australia
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Melbourne, 3004, Australia
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Murdoch, 6150, Australia
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South Brisbane, 4101, Australia
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Bruges, 8000, Belgium
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Charleroi, 6000, Belgium
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Kortrijk, 8500, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Roeselare, 8800, Belgium
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Barretos, 14784-400, Brazil
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Porto Alegre, 90020-090, Brazil
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Porto Alegre, 90470-340, Brazil
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Porto Alegre, 90610-000, Brazil
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Porto Alegre, 91350-200, Brazil
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Rio de Janeiro, 20231-050, Brazil
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Santa Maria, 97015-450, Brazil
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São José do Rio Preto, 15090-000, Brazil
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São Paulo, 01246-000, Brazil
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São Paulo, 01323-903, Brazil
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São Paulo, 01509-900, Brazil
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São Paulo, 03102-002, Brazil
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Edmonton, Alberta, T6G 1Z2, Canada
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Vancouver, British Columbia, V5Z 4E6, Canada
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London, Ontario, N6A 5W9, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Toronto, Ontario, M5G IX6, Canada
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Montreal, Quebec, H2X 0C2, Canada

Conditions

Explore the condition pages connected to this study.

MUSCLE INVASIVE BLADDER CANCER