Major trial tests new drug duo against standard bladder cancer treatment

NCT ID NCT05538663

Ongoing Disease control Sponsor: ECOG-ACRIN Cancer Research Group Source: ClinicalTrials.gov ↗

Summary

This large study is testing if a combination of two chemotherapy drugs (gemcitabine and docetaxel) works as well as the standard BCG treatment for a specific type of bladder cancer. It involves about 870 adults with high-grade, non-muscle invasive bladder cancer who have not had BCG before. The main goal is to see which treatment better keeps the cancer from coming back or getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Albany Medical Center

Albany, New York, 12208, United States
Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124, United States
Alegent Health Immanuel Medical Center

Omaha, Nebraska, 68122, United States
Alegent Health Lakeside Hospital

Omaha, Nebraska, 68130, United States
AnMed Health Cancer Center

Anderson, South Carolina, 29621, United States
Armes Family Cancer Center

Findlay, Ohio, 45840, United States
BASS Medical Group - Lennon

Walnut Creek, California, 94598, United States
Banner MD Anderson Cancer Center

Gilbert, Arizona, 85234, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

Houston, Texas, 77030, United States
Ben Taub General Hospital

Houston, Texas, 77030, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Bethesda North Hospital

Cincinnati, Ohio, 45242, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Billings Clinic-Cody

Cody, Wyoming, 82414, United States
Blanchard Valley Hospital

Findlay, Ohio, 45840, United States
Boulder Community Foothills Hospital

Boulder, Colorado, 80303, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
CARTI Cancer Center

Little Rock, Arkansas, 72205, United States
CHI Health Good Samaritan

Kearney, Nebraska, 68847, United States
CTCA at Western Regional Medical Center

Goodyear, Arizona, 85338, United States
Cancer Center at Saint Joseph's

Phoenix, Arizona, 85004, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Central Care Cancer Center - Bolivar

Bolivar, Missouri, 65613, United States
Central Care Cancer Center - Garden City

Garden City, Kansas, 67846, United States
Central Care Cancer Center - Great Bend

Great Bend, Kansas, 67530, United States
Cheyenne Regional Medical Center-West

Cheyenne, Wyoming, 82001, United States
Colorado Blood Cancer Institute

Denver, Colorado, 80218, United States
Commonwealth Cancer Center-Corbin

Corbin, Kentucky, 40701, United States
Community Hospital of Anaconda

Anaconda, Montana, 59711, United States
Community Medical Center

Missoula, Montana, 59804, United States
Community Medical Center

Toms River, New Jersey, 08755, United States
Contra Costa Regional Medical Center

Martinez, California, 94553-3156, United States
Cox Cancer Center Branson

Branson, Missouri, 65616, United States
CoxHealth South Hospital

Springfield, Missouri, 65807, United States
Creighton University Medical Center

Omaha, Nebraska, 68131, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
Dayton Physician LLC - Englewood

Dayton, Ohio, 45415, United States
Dayton Physicians LLC - Troy

Troy, Ohio, 45373, United States
Dayton Physicians LLC-Atrium

Franklin, Ohio, 45005, United States
Dayton Physicians LLC-Miami Valley South

Centerville, Ohio, 45459, United States
Dayton Physicians LLC-Wayne

Greenville, Ohio, 45331, United States
Delbert Day Cancer Institute at PCRMC

Rolla, Missouri, 65401, United States
FHCC South Lake Union

Seattle, Washington, 98109, United States
Fairbanks Memorial Hospital

Fairbanks, Alaska, 99701, United States
Flaget Memorial Hospital

Bardstown, Kentucky, 40004, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Fox Chase Cancer Center-Rockledge

Rockledge, Pennsylvania, 19046, United States
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
Freeman Health System

Joplin, Missouri, 64804, United States
George Washington University Medical Center

Washington D.C., District of Columbia, 20037, United States
Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220, United States
Good Samaritan Regional Health Center

Mount Vernon, Illinois, 62864, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Greater Dayton Cancer Center

Kettering, Ohio, 45409, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
Idaho Urologic Institute-Meridian

Meridian, Idaho, 83642, United States
Indu and Raj Soin Medical Center

Beavercreek, Ohio, 45431, United States
Jefferson Healthcare

Port Townsend, Washington, 98368, United States
Jersey City Medical Center

Jersey City, New Jersey, 07302, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Kalispell Regional Medical Center

Kalispell, Montana, 59901, United States
Karmanos Cancer Institute at McLaren Greater Lansing

Lansing, Michigan, 48910, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854, United States
Kootenai Clinic Cancer Services - Sandpoint

Sandpoint, Idaho, 83864, United States
Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814, United States
LSU Health Sciences Center at Shreveport

Shreveport, Louisiana, 71103, United States
LSU Healthcare Network / Metairie Multi-Specialty Clinic

Metairie, Louisiana, 70006, United States
Lake Regional Hospital

Osage Beach, Missouri, 65065, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone

New York, New York, 10016, United States
Lexington Medical Center

West Columbia, South Carolina, 29169, United States
Longmont United Hospital

Longmont, Colorado, 80501, United States
Los Angeles General Medical Center

Los Angeles, California, 90033, United States
Louisiana State University Health Science Center

New Orleans, Louisiana, 70112, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
MD Anderson League City

League City, Texas, 77573, United States
MD Anderson West Houston

Houston, Texas, 77079, United States
MD Anderson in Sugar Land

Sugar Land, Texas, 77478, United States
MD Anderson in The Woodlands

Conroe, Texas, 77384, United States
MUSC Health Florence Medical Center

Florence, South Carolina, 29505, United States
Maine Medical Partners Urology

South Portland, Maine, 04106, United States
Marjorie Weinberg Cancer Center at Loyola-Gottlieb

Melrose Park, Illinois, 60160, United States
Mary Bird Perkins Cancer Center

Baton Rouge, Louisiana, 70809, United States
Mary Greeley Medical Center

Ames, Iowa, 50010, United States
McFarland Clinic - Ames

Ames, Iowa, 50010, United States
McFarland Clinic - Boone

Boone, Iowa, 50036, United States
McFarland Clinic - Jefferson

Jefferson, Iowa, 50129, United States
McFarland Clinic - Marshalltown

Marshalltown, Iowa, 50158, United States
McFarland Clinic - Trinity Cancer Center

Fort Dodge, Iowa, 50501, United States
MedStar Georgetown University Hospital

Washington D.C., District of Columbia, 20007, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester

East White Plains, New York, 10604, United States
Mercy Cancer Center

Merced, California, 95340, United States
Mercy Cancer Center - Carmichael

Carmichael, California, 95608, United States
Mercy Cancer Center - Elk Grove

Elk Grove, California, 95758, United States
Mercy Cancer Center - Rocklin

Rocklin, California, 95765, United States
Mercy Cancer Center - Sacramento

Sacramento, California, 95816, United States
Mercy Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, 65401, United States
Mercy Health - Paducah Cancer Center

Paducah, Kentucky, 42003, United States
Mercy Hospital Fort Smith

Fort Smith, Arkansas, 72903, United States
Mercy Hospital Joplin

Joplin, Missouri, 64804, United States
Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital South

St Louis, Missouri, 63128, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy Hospital Washington

Washington, Missouri, 63090, United States
Mercy Medical Center

Durango, Colorado, 81301, United States
Mercy San Juan Medical Center

Carmichael, California, 95608, United States
Michael E DeBakey VA Medical Center

Houston, Texas, 77030, United States
Mission Hope Medical Oncology - Arroyo Grande

Arroyo Grande, California, 93420, United States
Mission Hope Medical Oncology - Santa Maria

Santa Maria, California, 93444, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
Moffitt Cancer Center - McKinley Campus

Tampa, Florida, 33612, United States
Moffitt Cancer Center at Wesley Chapel

Wesley Chapel, Florida, 33544, United States
Moffitt Cancer Center-International Plaza

Tampa, Florida, 33607, United States
Monmouth Medical Center

Long Branch, New Jersey, 07740, United States
Monmouth Medical Center Southern Campus

Lakewood, New Jersey, 08701, United States
Mount Sinai Hospital

New York, New York, 10029, United States
Mountain Blue Cancer Care Center - Swedish

Englewood, Colorado, 80113, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

New York, New York, 10032, United States
NYU Langone Hospital - Long Island

Mineola, New York, 11501, United States
Nebraska Medicine-Bellevue

Bellevue, Nebraska, 68123, United States
Nebraska Medicine-Village Pointe

Omaha, Nebraska, 68118, United States
North Shore Medical Center

Skokie, Illinois, 60076, United States
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026, United States
NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035, United States
Ochsner LSU Health - Cancer Treatment Center

Shreveport, Louisiana, 71106, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oncology Hematology Care Inc-Kenwood

Cincinnati, Ohio, 45236, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
Orion Cancer Care

Findlay, Ohio, 45840, United States
Pacific Central Coast Health Center-San Luis Obispo

San Luis Obispo, California, 93401, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Portland VA Medical Center

Portland, Oregon, 97239, United States
Presbyterian - Saint Lukes Medical Center - Health One

Denver, Colorado, 80218, United States
Prisma Health Greenville Memorial Hospital

Greenville, South Carolina, 29605, United States
Ralph H Johnson VA Medical Center

Charleston, South Carolina, 29401, United States
Reid Health

Richmond, Indiana, 47374, United States
Robert Wood Johnson University Hospital Somerset

Somerville, New Jersey, 08876, United States
Rocky Mountain Cancer Centers - Centennial

Centennial, Colorado, 80112, United States
Rocky Mountain Cancer Centers - Swedish

Englewood, Colorado, 80113, United States
Rocky Mountain Cancer Centers-Aurora

Aurora, Colorado, 80012, United States
Rocky Mountain Cancer Centers-Boulder

Boulder, Colorado, 80304, United States
Rocky Mountain Cancer Centers-Lakewood

Lakewood, Colorado, 80228, United States
Rocky Mountain Cancer Centers-Littleton

Littleton, Colorado, 80120, United States
Rocky Mountain Cancer Centers-Longmont

Longmont, Colorado, 80501, United States
Rocky Mountain Cancer Centers-Midtown

Denver, Colorado, 80218, United States
Rocky Mountain Cancer Centers-Penrose

Colorado Springs, Colorado, 80907, United States
Rocky Mountain Cancer Centers-Rose

Denver, Colorado, 80220, United States
Rocky Mountain Cancer Centers-Sky Ridge

Lone Tree, Colorado, 80124, United States
Rocky Mountain Cancer Centers-Thornton

Thornton, Colorado, 80260, United States
Rose Medical Center

Denver, Colorado, 80220, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Rutgers New Jersey Medical School

Newark, New Jersey, 07101, United States
Saint Alphonsus Cancer Care Center-Baker City

Baker City, Oregon, 97814, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605, United States
Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687, United States
Saint Alphonsus Cancer Care Center-Ontario

Ontario, Oregon, 97914, United States
Saint Anthony Hospital

Lakewood, Colorado, 80228, United States
Saint Anthony's Health

Alton, Illinois, 62002, United States
Saint Barnabas Medical Center

Livingston, New Jersey, 07039, United States
Saint Elizabeth Boardman Hospital

Boardman, Ohio, 44512, United States
Saint Elizabeth Youngstown Hospital

Youngstown, Ohio, 44501, United States
Saint Francis Cancer Center

Colorado Springs, Colorado, 80923, United States
Saint Joseph Hospital

Lexington, Kentucky, 40504, United States
Saint Joseph Hospital East

Lexington, Kentucky, 40509, United States
Saint Joseph London

London, Kentucky, 40741, United States
Saint Joseph Mount Sterling

Mount Sterling, Kentucky, 40353, United States
Saint Joseph Radiation Oncology Resource Center

Lexington, Kentucky, 40504, United States
Saint Joseph Warren Hospital

Warren, Ohio, 44484, United States
Saint Louis Cancer and Breast Institute-Ballwin

Ballwin, Missouri, 63011, United States
Saint Louis Cancer and Breast Institute-South City

St Louis, Missouri, 63109, United States
Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004, United States
Saint Mary's Hospital

Centralia, Illinois, 62801, United States
Saint Michael Cancer Center

Silverdale, Washington, 98383, United States
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Southwest Oncology PC

Durango, Colorado, 81301, United States
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
Swedish Medical Center

Englewood, Colorado, 80113, United States
The Melanoma and Skin Cancer Institute

Englewood, Colorado, 80113, United States
The Women's Imaging Center

Denver, Colorado, 80209, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
TriHealth Cancer Institute-Anderson

Cincinnati, Ohio, 45255, United States
TriHealth Cancer Institute-Westside

Cincinnati, Ohio, 45247, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UCSF Medical Center-Mission Bay

San Francisco, California, 94158, United States
UMass Memorial Medical Center - University Campus

Worcester, Massachusetts, 01655, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
UTMB Cancer Center at Victory Lakes

League City, Texas, 77573, United States
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Florida Health Science Center - Gainesville

Gainesville, Florida, 32610, United States
University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Minnesota/Masonic Cancer Center

Minneapolis, Minnesota, 55455, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pennsylvania/Abramson Cancer Center

Philadelphia, Pennsylvania, 19104, United States
University of Texas Medical Branch

Galveston, Texas, 77555-0565, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
Virginia Mason Medical Center

Seattle, Washington, 98101, United States
Walter Knox Memorial Hospital

Emmett, Idaho, 83617, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
Woodland Memorial Hospital

Woodland, California, 95695, United States

Conditions

Explore the condition pages connected to this study.

NON-MUSCLE INVASIVE BLADDER CANCER