New hope for advanced bladder cancer: experimental combos tested

NCT ID NCT07232602

First seen Nov 18, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tests whether adding new investigational drugs to the standard two-drug treatment (enfortumab vedotin plus pembrolizumab) can shrink tumors more safely in people with advanced bladder cancer that has spread. About 55 adults who have not had prior treatment for their advanced cancer will receive the standard therapy plus an extra experimental agent. The main goals are to check side effects and see how many patients' tumors shrink or disappear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center ( Site 5901)

    RECRUITING

    Seoul, 05505, South Korea

    Contact Phone: •••-•••-••••

  • CHU de Bordeaux Hop St ANDRE ( Site 5607)

    RECRUITING

    Bordeaux, Gironde, 33075, France

    Contact Phone: •••-•••-••••

  • Cleveland Clinic Taussig Cancer ( Site 5036)

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-••••

  • Erasmus MC ( Site 5303)

    RECRUITING

    Rotterdam, South Holland, 3015 GD, Netherlands

    Contact Phone: •••-•••-••••

  • FALP ( Site 5151)

    RECRUITING

    Santiago, Region M. de Santiago, 7500921, Chile

    Contact Phone: •••-•••-••••

  • Hospital Clinico San Carlos ( Site 5765)

    RECRUITING

    Madrid, 28040, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitari Vall de Hebron ( Site 5767)

    RECRUITING

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-••••

  • Huntsman Cancer Institute ( Site 5041)

    RECRUITING

    Salt Lake City, Utah, 84112-5550, United States

    Contact Phone: •••-•••-••••

  • Rabin Medical Center ( Site 5504)

    RECRUITING

    Petah Tikva, 4941492, Israel

    Contact Phone: •••-•••-••••

  • Rambam Health Care Campus ( Site 5501)

    RECRUITING

    Haifa, 3109601, Israel

    Contact Phone: •••-•••-••••

  • Samsung Medical Center ( Site 5902)

    RECRUITING

    Seoul, 06351, South Korea

    Contact Phone: •••-•••-••••

  • Severance Hospital, Yonsei University Health System ( Site 5903)

    RECRUITING

    Seoul, 03722, South Korea

    Contact Phone: •••-•••-••••

  • St Bartholomew s Hospital ( Site 5206)

    RECRUITING

    London, London, City of, EC1A 7BE, United Kingdom

    Contact Phone: •••-•••-••••

  • UCSF Medical Center at Mission Bay ( Site 5044)

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.