Major trial tests new drug duo against tough bladder cancer

NCT ID NCT03036098

Summary

This large, late-stage study is comparing new immunotherapy drug combinations against standard chemotherapy for people with advanced bladder cancer that has spread or cannot be removed by surgery. It enrolled over 1,300 patients who had not received prior treatment for their advanced disease. The main goal is to see if adding immunotherapies helps patients live longer or live longer without their cancer getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hattiesburg Clinic

    Hattiesburg, Mississippi, 39401, United States

  • Local Institution

    Moscow, 125367, Russia

  • Local Institution - 0001

    Anchorage, Alaska, 99503, United States

  • Local Institution - 0002

    Burnsville, Minnesota, 55337, United States

  • Local Institution - 0004

    Athens, Georgia, 30607, United States

  • Local Institution - 0005

    Capital Federal, Buenos Aires, 1426, Argentina

  • Local Institution - 0006

    Córdoba, 5004, Argentina

  • Local Institution - 0007

    Mar del Plata, Buenos Aires, 7600, Argentina

  • Local Institution - 0008

    Viedma, 8500, Argentina

  • Local Institution - 0009

    Buenos Aires, 1120, Argentina

  • Local Institution - 0010

    Santiago, Santiago Metropolitan, 8420383, Chile

  • Local Institution - 0012

    Viña del Mar, Región de Valparaíso, 2520598, Chile

  • Local Institution - 0013

    Pittsburgh, Pennsylvania, 15212, United States

  • Local Institution - 0014

    Mineola, New York, 11501, United States

  • Local Institution - 0016

    Florianópolis, Santa Catarina, 88034-000, Brazil

  • Local Institution - 0017

    Brasília, Federal District, 70200-730, Brazil

  • Local Institution - 0018

    Barretos, São Paulo, 14784-400, Brazil

  • Local Institution - 0019

    São José do Rio Preto, São Paulo, 15090-000, Brazil

  • Local Institution - 0020

    Porto Alegre, Rio Grande do Sul, 90610000, Brazil

  • Local Institution - 0021

    Ijuí, Rio Grande do Sul, 98700-000, Brazil

  • Local Institution - 0022

    Amsterdam, North Holland, 1066 CX, Netherlands

  • Local Institution - 0024

    Groningen, 9713 GZ, Netherlands

  • Local Institution - 0026

    Leeuwarden, 8934 AD, Netherlands

  • Local Institution - 0030

    Lima, 34, Peru

  • Local Institution - 0031

    Lima, 15076, Peru

  • Local Institution - 0032

    Kansas City, Missouri, 64111-3220, United States

  • Local Institution - 0033

    Thomasville, Georgia, 31792, United States

  • Local Institution - 0036

    Dresden, 01307, Germany

  • Local Institution - 0037

    Hanover, 30625, Germany

  • Local Institution - 0038

    Nuremberg, 90419, Germany

  • Local Institution - 0039

    Würzburg, 97080, Germany

  • Local Institution - 0040

    Tübingen, 72076, Germany

  • Local Institution - 0041

    Jena, 07747, Germany

  • Local Institution - 0042

    Chur, 7000, Switzerland

  • Local Institution - 0046

    Chicago, Illinois, 60612, United States

  • Local Institution - 0047

    Freiburg im Breisgau, 79106, Germany

  • Local Institution - 0048

    Essen, 45147, Germany

  • Local Institution - 0049

    Hamburg, 22763, Germany

  • Local Institution - 0051

    Boca Raton, Florida, 33486, United States

  • Local Institution - 0052

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Local Institution - 0053

    Halifax, Nova Scotia, B3H 2Y9, Canada

  • Local Institution - 0054

    Québec, Quebec, G1J 1Z4, Canada

  • Local Institution - 0055

    Enschede, 7512KZ, Netherlands

  • Local Institution - 0056

    Boston, Massachusetts, 02210, United States

  • Local Institution - 0057

    Manchester, New Hampshire, 03103, United States

  • Local Institution - 0058

    Lund, 221 85, Sweden

  • Local Institution - 0059

    Linköping, 581 85, Sweden

  • Local Institution - 0060

    Helsinki, 00029, Finland

  • Local Institution - 0061

    Baden, Canton of Aargau, 5404, Switzerland

  • Local Institution - 0062

    Jacksonville, Florida, 32256, United States

  • Local Institution - 0063

    Ann Arbor, Michigan, 48197, United States

  • Local Institution - 0064

    London, Ontario, N6A 4L6, Canada

  • Local Institution - 0065

    Madrid, 28034, Spain

  • Local Institution - 0066

    Madrid, 28041, Spain

  • Local Institution - 0067

    Seville, 41013, Spain

  • Local Institution - 0068

    Barcelona, 08025, Spain

  • Local Institution - 0069

    Valencia, 46009, Spain

  • Local Institution - 0070

    A Coruña, 15006, Spain

  • Local Institution - 0072

    New York, New York, 10029, United States

  • Local Institution - 0073

    Boston, Massachusetts, 02215, United States

  • Local Institution - 0074

    Bergen, 5021, Norway

  • Local Institution - 0075

    Jönköping, 553 05, Sweden

  • Local Institution - 0081

    Lorenskog, 1478, Norway

  • Local Institution - 0082

    Columbus, Ohio, 43210, United States

  • Local Institution - 0083

    Buffalo, New York, 14263, United States

  • Local Institution - 0084

    Albuquerque, New Mexico, 87131, United States

  • Local Institution - 0086

    Kirkland, Washington, 98034, United States

  • Local Institution - 0087

    Fort Lauderdale, Florida, 33308, United States

  • Local Institution - 0088

    Marseille, 13273, France

  • Local Institution - 0089

    Lille, 59000, France

  • Local Institution - 0090

    Saint-Priest-en-Jarez, 42271, France

  • Local Institution - 0091

    Nîmes, Gard, 30029, France

  • Local Institution - 0092

    Suresnes, 92151, France

  • Local Institution - 0093

    Tours, 37044, France

  • Local Institution - 0094

    Villejuif, 94805, France

  • Local Institution - 0095

    St Louis, Missouri, 63110, United States

  • Local Institution - 0096

    Waratah, New South Wales, 2298, Australia

  • Local Institution - 0099

    Westmead, New South Wales, 2145, Australia

  • Local Institution - 0100

    Doubleview, Western Australia, 6018, Australia

  • Local Institution - 0101

    Heidelberg, Victoria, 3084, Australia

  • Local Institution - 0102

    Athens, 115 28, Greece

  • Local Institution - 0103

    Ioannina, Ípeiros, 455 00, Greece

  • Local Institution - 0104

    Portland, Oregon, 97213, United States

  • Local Institution - 0106

    Vitacura, 0, Chile

  • Local Institution - 0107

    Milan, 20133, Italy

  • Local Institution - 0108

    Arezzo, 52100, Italy

  • Local Institution - 0109

    Grosseto, 58100, Italy

  • Local Institution - 0110

    Napoli, 80131, Italy

  • Local Institution - 0111

    Forlì, 47014, Italy

  • Local Institution - 0114

    Weiden, 92637, Germany

  • Local Institution - 0115

    Fresno, California, 93703, United States

  • Local Institution - 0116

    Durham, North Carolina, 27710, United States

  • Local Institution - 0117

    New Orleans, Louisiana, 70121, United States

  • Local Institution - 0119

    Passo Fundo, Rio Grande do Sul, 99010-080, Brazil

  • Local Institution - 0120

    Tugun, Queensland, 4224, Australia

  • Local Institution - 0124

    Seoul, 03080, South Korea

  • Local Institution - 0125

    Goyang-si, Gyeonggido, 10408, South Korea

  • Local Institution - 0126

    Seongnam-si, 13620, South Korea

  • Local Institution - 0127

    Seoul, 06351, South Korea

  • Local Institution - 0128

    Seoul, 05505, South Korea

  • Local Institution - 0129

    Mexico City, Mexico City, 06100, Mexico

  • Local Institution - 0130

    Tlalpan, Mexico City, 14080, Mexico

  • Local Institution - 0131

    Monterrey, Nuevo León, 64460, Mexico

  • Local Institution - 0134

    Córdoba, 5000, Argentina

  • Local Institution - 0135

    Chiba, Chiba, 260-8717, Japan

  • Local Institution - 0136

    Hirosaki, Aomori, 036-8563, Japan

  • Local Institution - 0137

    Kita-Gun, Kagawa-ken, 7610793, Japan

  • Local Institution - 0138

    Shinjuku-Ku, Tokyo, 1608582, Japan

  • Local Institution - 0139

    Sayama, Osaka, 589-8511, Japan

  • Local Institution - 0140

    Fukuoka, Fukuoka, 8128582, Japan

  • Local Institution - 0141

    Niigata, Niigata, 9518520, Japan

  • Local Institution - 0142

    Bunkyo-ku, Tokyo, 1138602, Japan

  • Local Institution - 0143

    Okayama, Okayama-ken, 7008558, Japan

  • Local Institution - 0144

    Osaka, Osaka, 5418567, Japan

  • Local Institution - 0145

    Takatsuki-shi, Osaka, 5698686, Japan

  • Local Institution - 0146

    Sapporo, Hokkaido, 0608543, Japan

  • Local Institution - 0147

    Matsuyama, Ehime, 7910280, Japan

  • Local Institution - 0148

    Bunkyo-ku, Tokyo, 1138519, Japan

  • Local Institution - 0149

    Adachi-ku, Tokyo, 1168567, Japan

  • Local Institution - 0150

    Tsukuba, Ibaraki, 3058576, Japan

  • Local Institution - 0151

    Seoul, 03722, South Korea

  • Local Institution - 0152

    Hradec Králové, 500 05, Czechia

  • Local Institution - 0154

    Mexico City, Mexico City, 07760, Mexico

  • Local Institution - 0155

    Taipei, 11217, Taiwan

  • Local Institution - 0156

    Kaohsiung City, 833, Taiwan

  • Local Institution - 0157

    Taoyuan District, 333, Taiwan

  • Local Institution - 0158

    Taipei, 100, Taiwan

  • Local Institution - 0159

    Taichung, 40705, Taiwan

  • Local Institution - 0160

    Brno, 656 53, Czechia

  • Local Institution - 0162

    Shanghai, Shanghai Municipality, 200032, China

  • Local Institution - 0163

    Shanghai, Shanghai Municipality, 200040, China

  • Local Institution - 0164

    Shanghai, 200032, China

  • Local Institution - 0167

    Shanghai, Shanghai Municipality, 200025, China

  • Local Institution - 0169

    Beijing, Beijing Municipality, 100034, China

  • Local Institution - 0170

    Beijing, 100083, China

  • Local Institution - 0171

    Beijing, Beijing Municipality, 100001, China

  • Local Institution - 0172

    Hangzhou, Zhejiang, 310014, China

  • Local Institution - 0173

    Hangzhou, Zhejiang, 0, China

  • Local Institution - 0174

    Hangzhou, Zhejiang, 310009, China

  • Local Institution - 0175

    Nanjing, Jiangsu, 0, China

  • Local Institution - 0176

    Nanjing, Jiangsu, 210008, China

  • Local Institution - 0177

    Nanjing, Jiangsu, 210000, China

  • Local Institution - 0180

    Wuhan, Hubei, 430030, China

  • Local Institution - 0182

    Chongqing, Chongqing Municipality, 400030, China

  • Local Institution - 0184

    Chengdu, Sichuan, 610041, China

  • Local Institution - 0186

    Changchun, Jilin, 130021, China

  • Local Institution - 0187

    Craiova, Dolj, 200542, Romania

  • Local Institution - 0188

    South Brisbane, Queensland, 4101, Australia

  • Local Institution - 0189

    Bydgoszcz, 85-796, Poland

  • Local Institution - 0190

    Aalborg, 9210, Denmark

  • Local Institution - 0191

    Cluj-Napoca, Cluj, 400015, Romania

  • Local Institution - 0192

    Singapore, Central Singapore, 168583, Singapore

  • Local Institution - 0193

    Izmir, 35340, Turkey (Türkiye)

  • Local Institution - 0194

    Ankara, 06590, Turkey (Türkiye)

  • Local Institution - 0196

    Herlev, 2730, Denmark

  • Local Institution - 0197

    Faenza, 48018, Italy

  • Local Institution - 0198

    Ramat Gan, 52621, Israel

  • Local Institution - 0199

    Kfar Saba, 44281, Israel

  • Local Institution - 0200

    Ube, Yamaguchi, 755-8505, Japan

  • Local Institution - 0201

    Hamamatasu, Shizuoka, 431-3192, Japan

  • Local Institution - 0202

    Warsaw, 02-781, Poland

  • Local Institution - 0204

    Istanbul, 34300, Turkey (Türkiye)

  • Local Institution - 0205

    Koszalin, 75-581, Poland

  • Local Institution - 0207

    Milford, Massachusetts, 01757, United States

  • Local Institution - 0208

    Boston, Massachusetts, 02215, United States

  • Local Institution - 0209

    Santander, 39008, Spain

  • Local Institution - 0213

    Mannheim, 68167, Germany

  • Local Institution - 0214

    Morioka, Iwate, 0208505, Japan

  • Local Institution - 0215

    Wakayama, Wakayama, 641-8510, Japan

  • Local Institution - 0216

    Yantai, Shandong, 264000, China

  • Local Institution - 0217

    Guiyang, Guizhou, 550002, China

  • Local Institution - 0219

    Harbin, Heilongjiang, 150000, China

  • Local Institution - 0220

    Taiyuan, Shan1xi, 030001, China

  • St Joseph Heritage Healthcare

    Santa Rosa, California, 95403, United States

Conditions

Explore the condition pages connected to this study.